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77516-53-1

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77516-53-1 Usage

Description

N-cyclohexyl-2-nitrobenzenesulphonamide, with the molecular formula C12H16N2O4S, is a chemical compound that serves various industrial applications due to its unique properties.

Uses

Used in Rubber Industry:
N-cyclohexyl-2-nitrobenzenesulphonamide is used as a rubber accelerator and vulcanizing agent for the production of rubber products, enhancing the efficiency and quality of the manufacturing process.
Used in Oil and Gas Industry:
In the oil and gas industry, N-cyclohexyl-2-nitrobenzenesulphonamide is utilized as a corrosion inhibitor, playing a crucial role in protecting equipment and infrastructure from the damaging effects of corrosive elements.
Used in Dye and Pigment Production:
N-cyclohexyl-2-nitrobenzenesulphonamide is used in the production of dyes and pigments, contributing to the development of a wide range of colorants for various applications.
Used in Pharmaceutical Industry:
This chemical compound is also employed in the production of pharmaceuticals, where it may contribute to the development of new drugs or the improvement of existing ones.
Safety Note:
N-cyclohexyl-2-nitrobenzenesulphonamide is classified as a harmful substance, and it is essential to handle it with care to avoid irritation to the skin, eyes, and respiratory system upon exposure. Proper safety measures should be taken during its use and storage.

Check Digit Verification of cas no

The CAS Registry Mumber 77516-53-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,1 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 77516-53:
(7*7)+(6*7)+(5*5)+(4*1)+(3*6)+(2*5)+(1*3)=151
151 % 10 = 1
So 77516-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O4S/c15-14(16)11-8-4-5-9-12(11)19(17,18)13-10-6-2-1-3-7-10/h4-5,8-10,13H,1-3,6-7H2

77516-53-1Downstream Products

77516-53-1Relevant articles and documents

Chemical Synthesis and Biological Effect on Xylem Formation of Xylemin and Its Analogues

Kadota, Isao,Kouno, Ryugo,Motose, Hiroyasu,Otsu, Taichi,Shinohara, Shiori,Takahashi, Taku,Takamura, Hiroyoshi

, (2020/04/30)

Xylemin (6) and its designed structural analogues 18–23, N-(4-aminobutyl)alkylamines, were synthesized by 2-nitrobenzenesulfonamide (Ns) strategy. Investigation of the improved synthesis of 20–23 resulted in the development of one-step synthesis of these analogues from the commercially available corresponding ketones. Biological assessment of the synthetic molecules elucidated that xylemin (6) and the analogue N-(4-aminobutyl)cyclopentylamine (21) promoted the expression level of thermospermine synthase ACAULIS5 (ACL5) and enhanced xylem formation. In addition, xylemin (6) was found to significantly promote lateral root formation, whereas xylemin analogues 18–23 including 21 did not. These results indicate that the analogue 21 has the potential as a novel inhibitor of thermospermine synthesis to work specifically in xylem differentiation.

2,4-DIAMINO-6,7-DIHYDRO-5H-PYRROLO[2,3]PYRIMIDINE DERIVATIVES AS FAK/Pyk2 INHIBITORS

-

Page/Page column 66, (2012/07/27)

The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/ or Pyk2 mediated disorder or disease.

Arenesulfonylheterocycles (I): Synthesis and reactions of 2-benzenesulfonyl-4,5-dichloropyridazin-3-ones with amines

Kweon, Deok-Heon,Kim, Ho-Kyun,Kim, Jeum-Jong,Chung, Hyun A.,Woo, Song Lee,Kim, Sung-Kyu,Yoon, Yong-Jin

, p. 203 - 211 (2007/10/03)

The direct sulfonylation of 4,5-dichloropyridazin-3-ones with some benzenesulfonyl chlorides in the presence of base in tetrahydrofuran gave only the corresponding N-sulfonylated product. The reaction of 2-benzenesulfonyl-4,5-dichloropyridazin-3-ones with some aliphatic amines under neutral conditions afforded 5-alkylamino-2-benzenesulfonyl-4-chloropyridazin-3-ones and/or the corresponding N-alkyl-benzenesulfonamides.

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