77516-54-2 Usage
Type of compound
sulfonamide derivative
Common use
carbonic anhydrase inhibitor in the treatment of glaucoma
Mechanism of action
inhibits carbonic anhydrase, reducing production of aqueous humor in the eye and decreasing intraocular pressure
Potential benefits
prevents damage to optic nerve, preserves eyesight
Investigated uses
potential treatment for certain types of cancer, potential anti-inflammatory agent
Caution
may have side effects and interactions with other drugs
Use under guidance of healthcare professional
Check Digit Verification of cas no
The CAS Registry Mumber 77516-54-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,1 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 77516-54:
(7*7)+(6*7)+(5*5)+(4*1)+(3*6)+(2*5)+(1*4)=152
152 % 10 = 2
So 77516-54-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O2S/c13-11-8-4-5-9-12(11)17(15,16)14-10-6-2-1-3-7-10/h4-5,8-10,14H,1-3,6-7,13H2
77516-54-2Relevant academic research and scientific papers
2,4-DIAMINO-6,7-DIHYDRO-5H-PYRROLO[2,3]PYRIMIDINE DERIVATIVES AS FAK/Pyk2 INHIBITORS
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Page/Page column 66-67, (2012/07/27)
The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/ or Pyk2 mediated disorder or disease.
