775292-86-9

Upstream product

• 145657-28-9 N-(5,5-dimethyl-3-oxo-cyclohexen-1-yl)-2-aminobenzonitrile 
• 126-81-8 dimedone 
• 1885-29-6 anthranilic acid nitrile 
• 130187-17-6 2-(5,5-dimethyl-3-oxocyclohexen-1-yl)aminobenzonitrile hydrochloride 
• 7447-39-4 copper(II) chloride 

Downstream Products

• 1179998-41-4 C₂₂H₂₀N₄ 

Relevant academic research and scientific papers

Synthesis of 4-methyl-2,3-disubstituted quinoline scaffolds via environmentally benign Fe(iii) catalysed sequential condensation, cyclization and aromatization of 1,3-diketone and 2-ethynylaniline

Environmentally benign Fe(iii)-catalysed sequential condensation, cyclization and aromatization of 1,3-diketone and 2-ethynylaniline derivatives to the substituted quinoline scaffolds with good to excellent yield in shorter reaction time is described. This journal is

Sulfuric acid-modified PEG-6000 (PEG-OSO3H): An efficient, bio-degradable and reusable polymeric catalyst for the solvent-free synthesis of poly-substituted quinolines under microwave irradiation

Sulfuric acid-modified polyethylene glycol 6000 (PEG-OSO3H) is applied as an efficient and eco-friendly polymeric catalyst for Friedlaender synthesis of poly-substituted quinolines from 2-aminoaryl ketones (or anthranilonitrile) and carbonyl compounds possessing a reactive methylene group under microwave irradiation and solvent-free conditions. The reactions are completed in short times, and the products are obtained in good to excellent yields. The Royal Society of Chemistry.

Synthesis and crystal structure of 7,8-dihydroquinolino[2,3-a]acridine derivatives

Novel 9-amino-3-substituted-1,2,3,4-acridin-1-one derivatives and 9,14-diamino-7-substituted-7,8-dihydroquinolino[2,3-a]acridine derivatives were synthesized by the condensation reaction of 5-substituted-1,3-cyclohexanedione with 2-aminobenzonitrile and s

9-aminoacridine derivatives possessing psychotropic, antiamnestic and lipid-regulative activity

"Derivatives of 9-aminoacridine characterized by psychothropic, antiamnestic and lipid-regulating activities". New chemical compounds derived of 9-aminoacridine with a general formula are presented: STR1 where R=H or CH3 R1 =H, CHsu

DERIVATIVES OF 9-AMINOACRIDINE HAVING PSYCHOTROPIC, ANTIAMNESTIC AND LIPID REGULATING PROPERTIES

New chemical compounds, derivatives of 9-aminoacridine of general formula (I) where R = H, CH3; R1 = H, CH3, Br; R2 = H, CH3; R3 = alkyl-C1-C5, arylmethyl, diethylaminoethyl; X = C = O, CHOH; Y = CH2; X + Y = CH = CH; and their salts with organic and non-organic acids. The desired compounds are obtained by interaction of substituted nitriles of antranyl acid with dimedone with subsequent cyclization of intermediate enaminonitriles into corresponding ketones of 9-aminoacridine after the reduction of which and of their derivatives alkylated or aralkylated on the 9-amino group, the corresponding alcohols are obtained, after hydration of which 9-amino-3,4-dihydroacridines are obtained. When experimented on animals, the said derivatives of 9-aminoacridine have shown psychotropic, antiamnestic and lipid regulating properties, as well as a lower toxicity in comparison with known preparations.

Acridine derivatives

A compound of the formula : wherein R1 is hydrogen, halogen, hydroxy, lower alkoxy, lower alkyl or mono(or di or tri)halo(lower)alkyl, and (in which R2 and R3 are each lower alkyl),and a pharmaceutically acceptable salt thereof, processes for their prepar