77532-15-1

Upstream product

• 99-91-2 para-chloroacetophenone 
• 85-44-9 phthalic anhydride 
• 399017-11-9 2-[3-hydroxy-3-(p-chlorophenyl)]-prop-1-ynyl benzyl alcohol 
• 50454-31-4 2-<3-(4-Chlorophenyl)-1,3-dioxopropyl>benzoic acid 
• 29805-11-6 1-(4-chlorophenyl)prop-2-yn-1-ol 
• 5159-41-1 2-iodobenzyl alcohol 

Relevant academic research and scientific papers

A convenient and highly regio and stereoselective method for the synthesis of (E)-3-alkylidene isobenzofuran-1(3H)-ones (phthalides)

2-Iodobenzyl alcohol on treatment with acetylenic carbinols in the presence of a palladium catalyst and copper(I) iodide as a co-catalyst afforded disubstituted alkynes. Jones oxidation of the disubstituted alkynes led to (E)-3-alkylidene isobenzofuran-1(

A Convenient Synthesis of 3-Phenacylidenephthalides

3-Phenacylidenephthalides were prepared by the dehydration of 2-(1,3-dioxo-3-phenylpropyl)benzoic acids, obtained in turn by the condensation of phthalic anhydride with acetophenones.