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Usage

Uses

Used in Organic Synthesis:
2-Hydroxy-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is used as a reagent in organic synthesis for its ability to facilitate the formation of carbon-carbon bonds. Its unique boron-containing ring structure allows for versatile reactions, making it a valuable component in creating complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Hydroxy-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is utilized as a key intermediate in the synthesis of various drugs. Its reactivity and structural features contribute to the development of new medicinal compounds with specific therapeutic properties.
Used in Agrochemical Development:
2-Hydroxy-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile also finds application in the agrochemical sector, where it serves as a building block for the creation of novel agrochemicals. Its role in this industry is crucial for the development of effective and environmentally friendly pesticides and other agricultural products.
Used in Specialty Chemicals Manufacturing:
2-Hydroxy-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is also used in the production of specialty chemicals, where its unique properties are harnessed to create high-value products for specific applications in various industries, such as materials science, coatings, and advanced composites.

Upstream product

• 611-20-1 salicylonitrile 
• 73183-34-3 bis(pinacol)diborane 
• 40530-18-5 5-bromo-2-hydroxybenzonitrile 

Relevant academic research and scientific papers

AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF

The present invention aims to provide a compound that: has an excellent cytotoxic action on cancer cells, excellent induction of BET protein degradation in cancer cells, and an excellent binding-inhibiting action on BET protein and acetylated histone; and is effective as an anti-cancer agent, a BET protein degradation-inducing agent, or a BET protein inhibiting agent. A compound indicated in general formula (I) or a pharmacologically acceptable salt thereof. {In the formula, each symbol is as outlined in the Description.}

Para-Selective, Iridium-Catalyzed C-H Borylations of Sulfated Phenols, Benzyl Alcohols, and Anilines Directed by Ion-Pair Electrostatic Interactions

Para C-H borylations (CHB) of tetraalkylammonium sulfates and sulfamates have been achieved using bipyridine-ligated Ir boryl catalysts. Selectivities can be modulated by both the length of the alkyl groups in the tetraalkylammonium cations and the substituents on the bipyridine ligands. Ion pairing, where the alkyl groups of the cation shield the meta C-H bonds in the counteranions, is proposed to account for para selectivity. The 4,4′-dimethoxy-2,2′-bipyridine ligand gave superior selectivities.

TOLL-LIKE RECEPTOR 8 (TLR8)-SPECIFIC ANTAGONISTS AND METHODS OF MAKING AND USES THEREOF

Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.

Microwave-assisted preparation of aryltetrazoleboronate esters

(Chemical Equation Presented) The addition of azido trimethylsilane to arylnitrileboronate esters is shown to proceed rapidly in dimethoxyethane to give aryltetrazoleboronate esters in moderate to good yields, with dibutyltin oxide as catalyst.