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Z-Orn(Msc)-ONp is a synthetic peptide derivative, where "Z" stands for the benzyloxycarbonyl group, a commonly used protecting group in peptide synthesis. "Orn" represents ornithine, an amino acid, and "Msc" denotes the methanesulfonyl group, which is a protecting group for the side chain of ornithine. "ONp" signifies the p-nitrophenyl ester group, which is used as a reporter group for monitoring the activity of proteases or other enzymes that cleave the peptide bond. Z-Orn(Msc)-ONp is often utilized in biochemical research to study enzyme kinetics, substrate specificity, and inhibitor design. It serves as a substrate for enzymes that cleave the peptide bond, and the release of the p-nitrophenol group upon cleavage can be easily quantified, making it a valuable tool in enzyme assays and drug discovery.

77549-20-3

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77549-20-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 77549-20-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,4 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77549-20:
(7*7)+(6*7)+(5*5)+(4*4)+(3*9)+(2*2)+(1*0)=163
163 % 10 = 3
So 77549-20-3 is a valid CAS Registry Number.

77549-20-3Downstream Products

77549-20-3Relevant academic research and scientific papers

Enzymatic synthesis of a peptide bond between a tryptic fragment of horse heart cytochrome c and a synthetic model peptide

Westerhuis, L. W.,Tesser, G. I.,Nivard, R. J. F.

, p. 400 - 403 (2007/10/02)

As a model study for the usefulness of the synthetic action of a proteinase in the semisynthesis of large polypeptides, a heme peptide, comprising the residues 1-38 of horse heart cytochrome-c and bearing protective functions on the ε-amino groups, was in

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