77550-57-3

Upstream product

• 14064-75-6 N,N-dimethylcrotonamide 
• 56579-86-3 2-(3,4-methylenedioxyphenyl)-1,3-dithiane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 77516-02-0 C₂₆H₃₁NO₅S₂ 
• 77516-03-1 (5S,6R,7S)-5-(3,4-Dimethoxy-phenyl)-7-methyl-8-oxo-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid dimethylamide 
• 77516-03-1 (5S,6R,7R)-5-(3,4-Dimethoxy-phenyl)-7-methyl-8-oxo-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid dimethylamide 
• 77516-04-2 (5S,6S,7R)-5-(3,4-Dimethoxy-phenyl)-7-methyl-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid dimethylamide 
• 3738-02-1 (±)-galcatin 
• 59985-35-2 4-((5R,6R,7S)-6,7-Dimethyl-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxol-5-yl)-2-methoxy-phenol 

Relevant academic research and scientific papers

TANDEM CONJUGATE ADDITION-α-ALKYLATION OF UNSATURATED AMIDES. SYNTHESIS OF 1-ARYLTETRALIN LIGNANS

The amide alcohols 5,6, obtained in one step from the sequential reaction of N,N-dimethylcrotonamide with dithiane 3 anion and aryl aldehyde 4, were efficiently converted into the lignans galcatin (2a) and isogalcatin (2b).