TANDEM CONJUGATE ADDITION-α-ALKYLATION OF UNSATURATED AMIDES. SYNTHESIS OF 1-ARYLTETRALIN LIGNANS

DOI: 10.1016/0040-4039(80)80150-X

Source and publish data:

Tetrahedron Letters p. 4827 - 4830 (1980)

Update date:2022-08-05

Topics:

Authors:

Mpango, G. B.

Snieckus, V.

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Article abstract of DOI:10.1016/0040-4039(80)80150-X

The amide alcohols 5,6, obtained in one step from the sequential reaction of N,N-dimethylcrotonamide with dithiane 3 anion and aryl aldehyde 4, were efficiently converted into the lignans galcatin (2a) and isogalcatin (2b).

Full text of DOI:10.1016/0040-4039(80)80150-X

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