77551-74-7

Upstream product

• 83-46-5 β-sitosterol 
• 178394-80-4 2α,3α-epoxy-24(R)-ethyl-5α-cholestan-6-one 
• 136319-13-6 (24R)-3α-bromo-5α-stigmastan-6-one 
• 28398-88-1 24(R)-ethyl-5α-cholest-2-en-6-one 
• 23670-94-2 stigmast-4-ene-3,6-dione 
• 64-19-7 acetic acid 
• 402593-59-3 (24R)-5α-stigmastane-3α,6β-diol 
• 16137-56-7 3,5,6-trihydroxysitostane 

Relevant academic research and scientific papers

SYNTHESIS OF 3α-HYDROXY-6-KETOBRASSINOSTEROIDS

The synthesis has been effected of the new brassinosteroids (22S,23S)-28-homotyphasterol, 24-epityphasterol, and (22S,23S)-24-epityphasterol, which belong to the 3α-hydroxy-6-oxosteroids.For obtaining (22S,23S)-28-homotyphasterol from stigmasterol, a new scheme of synthesis has been developed the key stages of which are the reduction of a 2α,3α-epoxy-6-ketone with lithium tetrahydroaluminate and the selective oxidation of the resulting 3α,6β-diol to the 3α-hydroxy-6-ketone.

SYNTHESIS OF NATURAL PHYTOSTEROIDS OF THE 6-KETOSTIGMASTANE SERIES AND COMPOUNDS RELATED TO THEM

Preparative methods of synthesizing a number of natural 6-ketosteroids and 6-alcohols related to them from β-sitosterol have been developed.

A LABDANE DITERPENOID AND STEROL FROM LAGERSTROEMIA LANCASTERI

A new labdane diterpenoid, lagerstronolide, having a β-substituted γ-butyrolactone moiety, and stimast-4-ene-3β,6α-diol were isolated together with sitosterol glucoside from Lagerstroemia lancasteri.The structures of the new compounds were determined by means of spectral and chemical analysis.This is the first report of labdane diterpenoid in the Lythraceae family.Key Word Index - Lagerstroemia lancasteri; Lythraceae; labdane diterpenoid; sterol; lagerstronolide; stigmast-4-ene-3β,6α-diol.