77556-44-6

Usage

Structure

pyridine derivative with a bromo-substituted pyrazole group

Application

pharmaceutical research and development

Biological activities

potential ligand for metal ions, building block for heterocyclic compounds

Importance

intermediate in production of pharmaceuticals and agrochemicals

Potential use

development of new materials, tool for organic synthesis

Upstream product

• 626-55-1 3-Bromopyridine 
• 2075-45-8 4-bromo-1H-pyrazole 
• 25700-12-3 3-(1H-pyrazol-1-yl)pyridine 

Downstream Products

• 1286202-05-8 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)pyridine 

Relevant academic research and scientific papers

NURR1 RECEPTOR MODULATORS

Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein.

HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF

The present invention provides herein is a heteroaryl compound or a stereoisomer, a geometric isomer, a tautomer, a racemate, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, as well as a pharmaceutical composition containing the compound disclosed herein. The present invention also provides herein is use of the compound or the pharmaceutical composition thereof disclosed herein in the manufacture of a medicine for treating autoimmune diseases or proliferative diseases.

Heterocyclic compounds as pesticides

The present application relates to novel heterocyclic compounds, to the use thereof for controlling animal pests, which include arthropods and especially insects, and to processes for preparing the novel compounds.

PESTICIDAL COMPOSTIONS AND PROCESSES RELATED THERETO

This document discloses pesticidal molecules having the following formula (“Formula One”): and processes related thereto.

Heterocyclic Compounds as Pesticides

The present application relates to the use of heterocyclic compounds, some of which are known, for controlling animal pests including arthropods and in particular insects, furthermore to novel heterocyclic compounds and to processes for their preparation.

Hetarylyrazoles. II. Reactions of Pyrazol-1'-ylpyridines

Pyrazol-1'-ylpyridines undergo electrophilic substitution reactions (bromination, chlorination and nitration) preferentially in the pyrazole ring.There is some evidence of the mutual influence of the pyrazole and the pyridine ring on the reactivity of the