7759-35-5 Usage
Uses
Used in Contraceptive Applications:
Nestoron is used as a progestin in a contraceptive vaginal ring for its androgenic and estrogenic properties, providing effective birth control.
Used in Hormone Therapy:
Nestoron is used in hormone therapy to study the impact of progestins on hepatic estrogen-sensitive proteins, potentially leading to improved treatment options for various hormonal imbalances.
Used in Pharmaceutical Research:
Nestoron is used as a subject of study to compare the androgenic and estrogenic properties of progestins, contributing to a better understanding of their effects and potential applications in contraception and hormone therapy.
Pharmacokinetics
Elcometrine is a member of the 19-norprogesterone class of pr ogestins. when administered subcuta neously (implant), intravaginally (vaginal ring), or transdermally, elcometrine is an exceptionally potent progestin. It is 100-fold more potent when administered subcutaneously than when delivered orally. Its oral bioavaiability is only 10%，with a half life of just 1 to 2 hours because of rapid metabolism. The C16 methylene functionality substantially increases its affinity for the progesterone receptor.
Clinical Use
Because of its antiestrogenic action, elcometrine also can be administered transdermally along with estradiol as a treatment for menopausal symptoms .
Check Digit Verification of cas no
The CAS Registry Mumber 7759-35-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,5 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7759-35:
(6*7)+(5*7)+(4*5)+(3*9)+(2*3)+(1*5)=135
135 % 10 = 5
So 7759-35-5 is a valid CAS Registry Number.
InChI:InChI=1/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1
