77607-75-1

Upstream product

• 114570-69-3 3-(2-furyl)-1-(4-methoxyphenyl)propen-1-one 
• 105-56-6 ethyl 2-cyanoacetate 
• 67449-75-6 ethyl (E)-2-cyano-3-(2-furyl)-2-propenoate 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 171071-09-3 Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[3-cyano-4-furan-2-yl-6-(4-methoxy-phenyl)-2-oxo-2H-pyridin-1-yl]-tetrahydro-pyran-3-yl ester 
• 171071-17-3 Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[3-cyano-4-furan-2-yl-6-(4-methoxy-phenyl)-2-oxo-2H-pyridin-1-yl]-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Synthesis of N-glycosylated pyridines as new antiviral agents

A series of 3-cyanopyridine glycosides have been synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV) replication in MT-4 cells. Among the 3-cyanopyridine glycosides 6-(p- methylphenyl) and 6-(p-aminophenyl) were the most selective inhibitors of HIV replication.

Malononitriles & Cyanoesters : Part VI - Synthesis of New Biologically Active Cyanopyridines

3-(2'-Furyl)- and 3-(2'-thienyl)-acrylophenones (I) react with malononitrile in the presence of ammonium acetate to give 2-amino-3-cyano-4,6-disubstituted-pyridines (II).The latter are hydrolysed with alkali to give the corresponding nicotinamides (IV).Th