Synthesis of N-glycosylated pyridines as new antiviral agents

Article abstract of DOI:10.1080/15257779508010701

A series of 3-cyanopyridine glycosides have been synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV) replication in MT-4 cells. Among the 3-cyanopyridine glycosides 6-(p- methylphenyl) and 6-(p-aminophenyl) were the most selective inhibitors of HIV replication.

Full text of DOI:10.1080/15257779508010701

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Nucleosides and Nucleotides
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Synthesis of N-Glycosylated Pyridines
as New Antiviral Agents
E. S. Ibrahim a , G. E.H. Elgemeie a b e , M. M. Abbasi c , Y. A.
Abbas d , M. A. Elbadawi c & A. M.E. Attia d
a Chemistry Department , Faculty of Science, Suez Canal
University , Egypt
b Chemistry Department , Faculty of Science, Cairo University
(Bani Suef Branch) , Egypt
c Chemistry Department , Faculty of Science, Tanta University ,
Egypt
d Chemistry Department , Faculty of Education, Tanta University
(Kafr El-Sheikh) , Egypt
e Chemistry Department , Faculty of Science, Qatar University ,
P.O.Box 2713, Doha, State of Qatar
Published online: 24 Sep 2006.
To cite this article: E. S. Ibrahim , G. E.H. Elgemeie , M. M. Abbasi , Y. A. Abbas , M. A. Elbadawi
& A. M.E. Attia (1995) Synthesis of N-Glycosylated Pyridines as New Antiviral Agents, Nucleosides
and Nucleotides, 14:6, 1415-1423, DOI: 10.1080/15257779508010701
To link to this article: http://dx.doi.org/10.1080/15257779508010701
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