77607-77-3Relevant academic research and scientific papers
Microwave-assisted synthesis of 2(1H)-pyridones and their glucosides as cell proliferation inhibitors
Al-Neyadi, Shaikha S.,Hassan, Ahmed H.,Abdou, Ibrahim M.
experimental part, p. 120 - 134 (2011/10/09)
A new series of substituted 2(1H)-pyridones (4a-i) and their glucosides (5, 6a-e) were prepared as potential agents against leukemia (HL-60) cells. Glucosides (5,6a-e) were synthesized using three independent methods. Microwave protocol as an ecologically
Malononitriles & Cyanoesters : Part VI - Synthesis of New Biologically Active Cyanopyridines
Latif, N.,Mishriky, N.,Girgis, N. S.
, p. 147 - 149 (2007/10/02)
3-(2'-Furyl)- and 3-(2'-thienyl)-acrylophenones (I) react with malononitrile in the presence of ammonium acetate to give 2-amino-3-cyano-4,6-disubstituted-pyridines (II).The latter are hydrolysed with alkali to give the corresponding nicotinamides (IV).Th
