77609-07-5Relevant articles and documents
Cu(II)-Promoted Cascade Synthesis of Fused Imidazo-Pyridine-Carbonitriles
Rakshit, Amitava,Dhara, Hirendra Nath,Alam, Tipu,Dahiya, Anjali,Patel, Bhisma K.
supporting information, p. 17504 - 17510 (2021/11/18)
A Cu(II)-promoted synthesis of an aza-fused N-heterocycle having a benz-imidazopyridine scaffold is developed via an addition-cyclization reaction followed by an Ullmann-type C-N coupling between o-iodoanilines and γ-ketodinitriles. This protocol features a broad substrate scope, giving products in 32-84% yields. The compounds show excellent photoluminescence properties having two absorption maxima in the region between 270-280 and 338-350 nm and emission maxima in the range of 502-533 nm. The HOMO-LUMO energy gap of 3.49-3.57 eV was determined using Gaussian 09 at the B3LYP/6-31G (d, p) basis set level. We also demonstrated a few postsynthetic modifications.
Visible-light-accelerated pd-catalyzed cascade addition/ cyclization of arylboronic acids to γ- And β-ketodinitriles for the construction of 3-cyanopyridines and 3-cyanopyrrole analogues
Patel, Bhisma K.,Rakshit, Amitava,Kumar, Prashant,Alam, Tipu,Dhara, Hirendranath
, p. 12482 - 12504 (2020/11/09)
The one-pot synthetic strategies for 2,4,6-triarylnicotinonitriles and 2,5-diaryl-1H-pyrrole-3-carbonitriles have been accomplished via a Pd-catalyzed coupling of arylboronic acid with 2-(3-oxo-1,3-diarylpropyl)malononitrile and 2-(2-oxo-2- arylethyl)malo
One-Pot Quinine-Catalyzed Synthesis of α-Chiral γ-Keto Esters: Enantioenriched Precursors of cis-α,γ-Substituted-γ-Butyrolactones
Meninno, Sara,Volpe, Chiara,Lattanzi, Alessandra
supporting information, p. 2845 - 2848 (2016/09/13)
A highly enantioselective one-pot synthesis of important building blocks, α-chiral γ-keto esters, has been developed by combining a quinine-catalyzed Michael addition of malononitrile to trans-enones followed by magnesium monoperoxyphthalate (MMPP) oxidat
Conjugate addition of malononitrile on chalcone: Biocatalytic [Formula presented] bond formation
Punyapreddiwar, Nitesh D.,Zodape, Sangesh P.,Wankhade, Atul V.,Pratap, Umesh R.
, p. 124 - 126 (2016/08/23)
An efficient, cost effective and environmentally friendly protocol has been developed for the Michael addition of malononitrile on 1,3-diaryl-2-propen-1-ones (Chalcones) using very cheaper, easily available natural catalyst, baker's yeast. The whole cells of yeast excellently worked in nonaqueous medium, ethanol without decrease in catalytic activity.
Immobilization of lipase on Fe3O4/ZnO core/shell magnetic nanoparticles and catalysis of Michael-type addition to chalcone derivatives
Ghasemi, Sabrieh,Heidary, Marjan,Faramarzi, Mohammad Ali,Habibi, Zohreh
, p. 121 - 128 (2014/01/23)
Fe3O4/ZnO core/shell magnetic nanoparticles in 1:1 and 1:2 molar ratios were prepared and characterized by using X-ray powder diffraction, scanning electron microscopy, thermogravimetric analysis, FT-IR spectra, and flame atomic abso
A mild and convenient one-pot synthesis of 4,6-diaryl- 3-aminoisoxazolo[3, 4-b]pyridines
Miao, Chun-Bao,Wang, Yan-Hong,Dong, Chun-Ping,Yang, Hai-Tao,Meng, Qi,Sun, Xiao-Qiang
, p. 2599 - 2605 (2014/01/06)
We have developed a convenient method for the synthesis of a series of new 4,6-diaryl-3-aminoisoxazolo[3,4-b]pyridines through one-pot reaction starting from the easily available chalcones, malononitrile, and hydroxylamine. This class of compounds might h
An active and selective heterogeneous catalytic system for Michael addition
Keipour, Hoda,Khalilzadeh, Mohammad A.,Hosseini, Abolfazl,Pilevar, Afsaneh,Zareyee, Daryoush
experimental part, p. 537 - 540 (2012/06/29)
Potassium fluoride doped natural zeolite was found to be an efficient and selective solid base catalyst for 1,4-Michael addition. The catalyst is easily prepared and the workup procedure simplified by simple filtration. All products were obtained in high
The Michael addition of active methylene compounds to chalcone derivatives using a catalytic amount of iodine and K2CO3 at room temperature
Ren, Yi-Ming,Cai, Chun
experimental part, p. 176 - 178 (2011/07/31)
A convenient method for the Michael addition of active methylene compounds to chalcone derivatives has been developed using the inexpensive and environmentally friendly reagent I2/K2CO3 at room temperature. The method is m
A facile and efficient one-pot synthesis of polysubstituted benzenes in guanidinium ionic liquids
Xin, Xin,Wang, Yan,Xu, Wu,Lin, Yingjie,Duan, Haifeng,Dong, Dewen
body text, p. 893 - 898 (2010/09/05)
A facile and efficient synthesis of polysubstituted benzenes has been developed via sequential Michael addition, Knoevenagel condensation and nucleophilic cyclization reactions of readily available chalcones with active methylene compounds in guanidinium
Back to natural cinchona alkaloids: Highly enantioselective Michael addition of malononitrile to enones
Russo, Alessio,Perfetto, Alessandra,Lattanzi, Alessandra
supporting information; experimental part, p. 3067 - 3071 (2010/04/06)
An efficient and convenient highly enantioselective Michael addition of malononitrile to enones has been developed by using quinine as the organocatalyst. The adducts were isolated in excellent yield and high asymmetric induction (up to 95% ee). An easy r