77616-97-8 Usage
Uses
Used in Pharmaceutical Industry:
3-Amino-6-bromo-4-(2-pyridinyl)quinolin-2(1H)-one is used as an impurity in the production of Bromazepam, a benzodiazepine derivative with anxiolytic and sedative-hypnotic effects. The presence of 3-AMino-6-broMo-4-(pyridin-2-yl)quinolin-2(1H)-one in Bromazepam is significant as it may contribute to the overall pharmacological profile of the drug, potentially affecting its efficacy, safety, and side effects.
As an impurity, it is essential to monitor and control the levels of 3-Amino-6-bromo-4-(2-pyridinyl)quinolin-2(1H)-one in Bromazepam to ensure the quality, safety, and therapeutic benefits of the drug. This may involve the development of analytical methods and quality control measures to detect and quantify the presence of this impurity in the final product.
In addition to its role as an impurity in Bromazepam, further research may be conducted to explore the potential applications of 3-Amino-6-bromo-4-(2-pyridinyl)quinolin-2(1H)-one in other areas of pharmaceutical chemistry, such as the development of new drugs or drug delivery systems. The unique molecular structure of 3-AMino-6-broMo-4-(pyridin-2-yl)quinolin-2(1H)-one may offer opportunities for novel interactions with biological targets, potentially leading to the discovery of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 77616-97-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,6,1 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77616-97:
(7*7)+(6*7)+(5*6)+(4*1)+(3*6)+(2*9)+(1*7)=168
168 % 10 = 8
So 77616-97-8 is a valid CAS Registry Number.
77616-97-8Relevant academic research and scientific papers
New Synthesis of 7-Bromo-1,3-dihydro-3-hydroxy-5-(2'-pyridyl)-2H-1,4-benzoazepin-2-one
Kovac, Tomislav,Belin, Branka,Fajdiga, Tatjana,Sunjic, Vitomir
, p. 59 - 62 (2007/10/02)
A new synthesis of 7-bromo-1,3-dihydro-3-hydroxy-5-(2'-pyridyl)-2H-1,4-benzoazepin-2-one (5) is described.Starting from bromazepam (3), C(3) acylation with lead tetraacetate/potassium iodide in acetic acid affords 4, while its mild hydrolysis according ou
