77629-06-2Relevant academic research and scientific papers
New Methodology for the Synthesis of Protected, Primary Pentadienylamines
Connel, Richard D.,Helquist, Paul,Akermark, Bjoern
, p. 3359 - 3370 (2007/10/02)
The utility of forming N-tert-butoxycarbonyl- (Boc) and N-phthalimido-protected primary 2(E),4(E)-pentadienylamines from aldehydes and ketones is described.When diethyl -2-buten-1-yl>phosphonate (33E) is treated with s
Highly Stereoselective Route to (E)-Allyl Amines via Vinyltri-n-butylphosphonium Salts (Schweizer Reaction)
Meyers, A. I.,Lawson, Jon P.,Carver, David R.
, p. 3119 - 3123 (2007/10/02)
The reaction of vinyltri-n-butylphosphonium salts, aldehydes, and sodiophthalimide in THF gave good yields of the allylic phthalimides with high E stereoselectivity (75-100percent).The use of the vinyltriphenylphosphonium salts (Schweizer reaction) gave the allyl phthalimide with the Z isomer predominating.A study of the phthalimide cation and the effect of added lithium salt showed some reversal in the olefin geometry but in general the selectivity was only 3:1
