77637-40-2Relevant articles and documents
Hypervalent Iodine Oxidation of N-Acylhydrazones and N-Phenylsemicarbazone: An Efficient Method for the Synthesis of Derivatives of 1,3,4-Oxadiazoles and Δ3-1,3,4-Oxadiazolines
Yang, Rui-Yang,Dai, Li-Xin
, p. 3381 - 3383 (2007/10/02)
The oxidation of ketone N-acylhydrazones 1 by phenyliodine(III) diacetate (PIDA) in alcohol gave 2-alkoxy-Δ3-1,3,4-oxadiazolines 4 in excellent yields, while the oxidative cyclization of aldehyde N-acylhydrazone 2 by PIDA in methanolic sodium acetate gave 2,5-disubstituted 1,3,4-oxadiazoles in good yields.The oxidation of acetone 4-phenylsemicarbazone afforded 2-(N-phenylimino)-Δ3-1,3,4-oxadiazoline in excellent yield.