77637-40-2

Upstream product

• 78002-37-6 acetone 4-phenylsemicarbazone 

Downstream Products

• 134209-89-5 1,7,8-triaza-6,6-dimethyl-5-oxa-2-oxo-1,3,3-triphenylspiro<3.4>oct-7-ene 
• 1087654-07-6 7,7-dimethyl-3,3-pentamethylene-1-phenyl-8-oxa-1,5,6-triazaspiro[3.4]oct-5-en-2-one 
• 1332480-28-0 3,3-diethyl-4-(5-methyl-3-(6-methylpyridin-2-ylimino)-imidazo[1,2-a]pyridin-2(3H)-ylidene)-1-phenylazetidin-2-one 
• 1087653-95-9 3,3-diethyl-7,7-dimethyl-1-phenyl-8-oxa-1,5,6-triazaspiro[3.4]oct-5-en-2-one 
• 1087654-06-5 7,7-dimethyl-3,3-tetramethylene-1-phenyl-8-oxa-1,5,6-triazaspiro[3.4]oct-5-en-2-one 
• 134210-01-8 4-aza-1,2-bis(methoxycarbonyl)-5-oxo-4,6,6-triphenylspiro<2.2>hex-1-ene 
• 134210-00-7 4-Methoxy-1,3,3-triphenylazetidin-2-one 
• 134209-99-7 6-Phenoxy-1,4-diphenyl-4-aza-spiro[2.3]hexan-5-one 

Relevant academic research and scientific papers

Hypervalent Iodine Oxidation of N-Acylhydrazones and N-Phenylsemicarbazone: An Efficient Method for the Synthesis of Derivatives of 1,3,4-Oxadiazoles and Δ3-1,3,4-Oxadiazolines

The oxidation of ketone N-acylhydrazones 1 by phenyliodine(III) diacetate (PIDA) in alcohol gave 2-alkoxy-Δ3-1,3,4-oxadiazolines 4 in excellent yields, while the oxidative cyclization of aldehyde N-acylhydrazone 2 by PIDA in methanolic sodium acetate gave 2,5-disubstituted 1,3,4-oxadiazoles in good yields.The oxidation of acetone 4-phenylsemicarbazone afforded 2-(N-phenylimino)-Δ3-1,3,4-oxadiazoline in excellent yield.

β-Lactam-4-ylidenes

β-Lactam-4-ylidenes, generated by thermolysis of easily accessible spiro-fused β-lactam oxadiazolines, are trapped in typical intramolecular and intermolecular carbene reactions.