77657-94-4Relevant academic research and scientific papers
A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent
Anselmi, Silvia,Liu, Siyu,Kim, Seong-Heun,Barry, Sarah M.,Moody, Thomas S.,Castagnolo, Daniele
, p. 156 - 161 (2021/01/14)
A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.
Facile oxidation of sulfides to sulfoxides using sodium hypochlorite and oxoammonium salt as a catalyst: Chemo- and diastereoselective transformation of bis(phenylthio)alkanes into sulfoxides
Siedlecka,Skarzewski
, p. 401 - 404 (2007/10/02)
A facile and selective method for the title transformation is described. The two-phase oxidation of disulfides with one or two equivalents of sodium hypochlorite mediated by TEMPO and cocatalyzed by potassium bromide and PTC leads to the corresponding mon
Neighboring Group Participation in the Oxidation of Hydroxy Sulfides. Control of the Reaction Courses and Products
Ueno, Yoshio,Miyano, Tadaaki,Okawara, Makoto
, p. 3615 - 3618 (2007/10/02)
Oxidation of the hydroxy sulfides with hexabutyldistannoxane (HBD)-bromine system was studied in order to clarify neighboring group participation during the course of reaction.The oxidation products were found to be highly dependent on
