77657-95-5Relevant academic research and scientific papers
A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent
Anselmi, Silvia,Liu, Siyu,Kim, Seong-Heun,Barry, Sarah M.,Moody, Thomas S.,Castagnolo, Daniele
supporting information, p. 156 - 161 (2021/01/14)
A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.
Catalyst-free oxidation of sulfides to sulfoxides and diethylamine catalyzed oxidation of sulfides to sulfones using Oxone as an oxidant
Kupwade,Khot,Lad,Desai,Wadgaonkar
, p. 6875 - 6888 (2017/10/06)
Abstract: We describe here our journey from the failure of our attempts in controlled oxidation of sulfides to sulfoxides using an Oxone–KBr combination to our success in the development of a catalyst-free protocol for the oxidation of sulfides to sulfoxides using Oxone as an oxidant. We also describe the failure of our attempts at the oxidation of sulfides to sulfones using an excess of Oxone–KBr as well as Oxone, and our success towards the development of a rapid, scalable and chromatography-free protocol for the oxidation of sulfides to sulfones using diethylamine–Oxone as an unprecedented catalyst–oxidant combination.
Nickel ferrite nanoparticles-hydrogen peroxide: A green catalyst-oxidant combination in chemoselective oxidation of thiols to disulfides and sulfides to sulfoxides
Kulkarni, Aparna M.,Desai, Uday V.,Pandit, Kapil S.,Kulkarni, Makarand A.,Wadgaonkar, Prakash P.
, p. 36702 - 36707 (2014/12/10)
Nickel ferrite nanoparticles-hydrogen peroxide has been demonstrated for the first time as a green and efficient catalyst-oxidant combination in the chemoselective oxidation of thiols to disulfides and sulfides to sulfoxides. This magnetically separable catalyst was found to be reusable for five consecutive runs without appreciable change in the activity, as well as composition of the catalyst. The mechanism for the oxidation of thiols and sulfides has also been proposed. the Partner Organisations 2014.
Metal-free chemoselective oxidation of sulfides to sulfoxides by hydrogen peroxide catalyzed by in situ generated dodecyl hydrogen sulfate in the absence of organic co-solvents
Firouzabadi,Iranpoor,Jafari,Riazymontazer
, p. 434 - 438 (2007/10/03)
The mild oxidation of sulfides to sulfoxides with an aqueous solution of H2O2 (35%) catalyzed by in situ generated dodecyl hydrogen sulfate as Bronsted acid surfactant in the absence of any organic cosolvents and under metal-free con
Neighboring Group Participation in the Oxidation of Hydroxy Sulfides. Control of the Reaction Courses and Products
Ueno, Yoshio,Miyano, Tadaaki,Okawara, Makoto
, p. 3615 - 3618 (2007/10/02)
Oxidation of the hydroxy sulfides with hexabutyldistannoxane (HBD)-bromine system was studied in order to clarify neighboring group participation during the course of reaction.The oxidation products were found to be highly dependent on
