77663-56-0Relevant academic research and scientific papers
REACTIONS OF ETHYLENEDIAMINE AND ETHANOLAMINE WITH ACETYLENIC ESTERS AND KETONES
Basyouni, M. N.,Fouli, F. A.
, p. 235 - 239 (2007/10/02)
Ethylenediamine (IIa) reacts with methyl 3-aryl-propynoates (IIIa-c) and aryl-(2-phenylethynyl)ketones (VIa, b) to give the corresponding N,N'-ethylenebis-(3-arylpropynoic amides) (IVa-c) and (Z,Z)-N,N'-ethylenebis(3-amino-1-aryl-3-phenyl-2-propen-1-ones) (VIIa, b), respectively.However, excess IIa and IIIa gave N-(2-aminoethyl)-3-phenylpropynoic amide (V).Similarly, ethanolamine (IIb) gave with the ester (IIIb), N-(2-hydroxyethyl)-3-(p-chlorophenyl)propynoic amide (VIII) and with the ketones (VIa, b), the corresponding (Z)-3-amino-1-aryl-N-(2-hydroxyethyl)-3-phenyl-2-propen-1-ones (IXa, b).
