77664-95-0

Basic information

• Product Name: 1-CHLORO-7-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE
• Synonyms: 1-CHLORO-7-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE
• CAS NO: 77664-95-0
• Molecular Formula: C₁₂H₁₁ClO₂
• Molecular Weight: 222.67
• Mol File: 77664-95-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-CHLORO-7-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-7-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE(77664-95-0)
• EPA Substance Registry System: 1-CHLORO-7-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE(77664-95-0)

Safety Data

• Hazardous Substances Data: 77664-95-0(Hazardous Substances Data)

Usage

General Description

1-CHLORO-7-METHOXY-3,4-DIHYDRO-NAPHTHALENE-2-CARBALDEHYDE is a chemical compound that belongs to the class of aldehydes. It is a derivative of naphthalene, which is a polycyclic aromatic hydrocarbon. The compound contains a chloro group and a methoxy group attached to the naphthalene ring, as well as an aldehyde functional group. Its chemical structure suggests that it could potentially be used in various organic synthesis reactions. Additionally, it may have applications in the field of organic chemistry and chemical research due to its unique structure and reactivity. Further research and exploration of its potential uses and properties may be warranted.

Upstream product

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Downstream Products

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Relevant articles and documents

Synthesis and Resolution of Substituted [5]Carbohelicenes

Three types of racemic [5]helicenyl acetates (1a, 2, and 3a) were synthesized. The synthesis of 2 was achieved by regioselective oxidation using o-iodoxybenzoic acid. The enzymatic kinetic resolution of 1a-3a was studied. The conversion with the highest rate and ee was obtained using 1a as the substrate and lipase Amano PS-IM as the enzyme. The two enantiomers of 1-[5]helicenol 3b were separated using (1S)-10-camphorsulfonyl chloride as the chiral resolving agent.

Efficient Enantioselective Synthesis of Oxahelicenes Using Redox/Acid Cooperative Catalysts

An efficient and enantioselective synthesis of oxa[9]helicenes has been established via vanadium(V)-catalyzed oxidative coupling/intramolecular cyclization of polycyclic phenols. A newly developed vanadium complex cooperatively functions as both a redox and Lewis acid catalyst to promote the present sequential reaction and afford oxa[9]helicenes in good yields with up to 94% ee.

SUBSTITUTED THIOPHENE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION

The present invention provides substituted thiophene carboxamide compounds having structural Formula I and isomers, tautomers, polymorphs, carriers, prodrugs, and pharmaceutically acceptable salts thereof, compositions comprising such, and methods for treating diseases associated with kinase activity. More specifically, the present invention provides methods of treatment of a variety of diseases associated with IKK2 including the treatment of inflammation, other inflammation-associated disorders, such as, as an analgesic in the treatment of pain and headaches, arthritis, including but not limited to rheumatoid arthritis, asthma, gastrointestinal conditions such as inflammatory bowel disease, vascular diseases, viral infections such as AIDS, and cancer.