77667-99-3

Upstream product

• 72200-51-2 2,3:5,6-Di-O-isopropylidene-4-O-(3',4'-O-isopropylidene-β-D-galactopyranosyl)-aldehydo-D-glucose dimethyl acetal 
• 77667-93-7 6-O-benzoyl-3,4-O-isopropylidene-β-D-galactopyranosyl-(1->4)-2,3;4,6-di-O-isopropylidene-D-glucose dimethyl acetal 
• 211801-54-6 p-methylphenyl 2,3,4-tri-O-benzyl-1-thio-β-L-fucopyranoside 
• 98-88-4 benzoyl chloride 
• 33639-77-9 perbenzyl fucosyl bromide 

Downstream Products

• 77668-00-9 O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-(1→2)-O-(3,4-isopropylidene-β-D-galactopyranosyl)-(1→4)-2,3:5,6-di-O-isopropylidene-D-glucose dimethyl acetal 

Relevant academic research and scientific papers

METHOD FOR THE SYNTHESIS OF A TRISACCHARIDE

The present invention relates to an improved synthesis of a trisaccharide of the formula (1), novel intermediates used in the synthesis and the preparation of the intermediates.

Bi- to tetravalent glycoclusters: Synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity

The emerging functional versatility of cellular glycans makes research on the design of synthetic inhibitors a timely topic. In detail, the combination of ligand (or headgroup or contact site) structure with spatial parameters that depend on topological a

Bi- to tetravalent glycoclusters: Synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity

The emerging functional versatility of cellular glycans makes research on the design of synthetic inhibitors a timely topic. In detail, the combination of ligand (or headgroup or contact site) structure with spatial parameters that depend on topological a

SYNTHESIS OF 2'-O-FUCOSYLLACTOSE

The present invention relates to an improved synthesis of a trisaccharide of the formula (1), novel intermediates used in the synthesis and the preparation of the intermediates.

SYNTHESIS OF O-α-L-FUCOPYRANOSYL-(1->2)-O-β-D-GALACTOPYRANOSYL-(1->4)-D-GLUCOPYRANOSE (2'-O-α-L-FUCOPYRANOSYL-LACTOSE)

Selective benzoylation of 2,3:5,6:3',4'-tri-O-isopropylidenelactose dimethyl acetal (1) with benzoyl chloride in dichloromethane afforded the 6'-O-benzoyl derivative (2).The constitution of 2 was inferred from its n.m.r. spectrum, and confirmed by methyla