77670-54-3Relevant academic research and scientific papers
Pd(ii)-SDP-catalyzed enantioselective 5-exo-dig cyclization of γ-alkynoic acids: Application to the synthesis of functionalized dihydofuran-2(3H)-ones containing a chiral quaternary carbon center
Sridharan, Vellaisamy,Fan, Lulu,Takizawa, Shinobu,Suzuki, Takeyuki,Sasai, Hiroaki
supporting information, p. 5936 - 5943 (2013/09/12)
The Pd(ii)-SDP-catalyzed first enantioselective intramolecular cyclization of α,α-disubstituted γ-alkynoic acids is described. This 5-exo-dig cyclization afforded dihydrofuran-2(3H)-ones bearing a chiral quaternary carbon center in excellent yields with e
Copper/iron-cocatalyzed highly selective tandem reactions: Efficient approaches to Z-γ-alkylidene lactones
Li, Si,Jia, Wei,Jiao, Ning
supporting information; experimental part, p. 569 - 575 (2009/12/05)
Inexpensive copper/iron-cocatalyzed, efficient, highly regioselective and stereoselective onepot tandem conjugate addition-cyclization-hydrolysis- decarboxylation reactions have been developed, which provide efficient tandem reactions for C-C and C-O bond
Cyclisation of Acetylenecarboxylic Acid. Synthesis of γ-Methylenebutyrolactones
Yamamato, Makoto
, p. 582 - 587 (2007/10/02)
Various γ-exo-methylenebutyrolactones have been synthesized in excellent yield by the cyclisation of acetylenecarboxylic acids in the presence of a catalytic amount of mercury(II) oxide.Cyclisation of terminal acetylene compounds proceeded regioselectively to give γ-exo-methylenebutyrolactones as the sole product.Disubstituted acetylenes also gave the (Z)-configurational enol lactone, but small amounts of an (E)-isomer of a γ-exo-enol lactone and a δ-lactone (α-pyrone) were also formed.Spectral properties and stereochemistry of the exo-enol lactones are also discussed.
