77670-74-7

Upstream product

• 937-32-6 4-nitrobenzenesulfenyl chloride 
• 1021877-48-4 (+)-(1R,5S)-7,7-dichlorobicyclo[3.2.0]hept-2-en-6-one 

Downstream Products

• 77670-81-6 methyl 4-chloro-c-2-(dichloromethyl)-t-3-(4-nitrophenylthio)cyclopentane-r-1-carboxylate 
• 77670-81-6 methyl t-4-chloro-t-2-(dichloromethyl)-c-3-(4-nitrophenylthio)cyclopentane-r-1-carboxylate 
• 77670-82-7 c-4-chloro-c-2-(dichloromethyl)-r-1-piperidinocarbonyl-t-3-(4-nitrophenylthio)cyclopentane 

Relevant academic research and scientific papers

Stereocontrolled Addition of Some Sulphenyl Halydes to Bicyclohept-2-en-6-ones and Modification of the Adducts

The bicycloheptenones (1) and (2) reacted with the sulphenyl chlorides (13)-(15) in a highly regioselective manner to give the corresponding adducts (3)-(8) on 77-92percent yield. m-Chloroperoxybenzoic acid oxidation of the ketone (5) led to products (9), (10), and (23) resulting from oxidation at sulphur and/or Bayer-Villiger ring expansion.The corresponding dichloroketone (8) suffers oxidation at sulphur only to give the sulphoxide (11) and the sulphone (12).The 7,7-dichlorobicyclohept-6-one (8) yielded tetra-substituted cyclopentane derivatives (18)-(21) of defined stereochemistry on addition of methanol or piperidine across the C6-C7 bond