77674-99-8

Usage

Uses

Used in Agricultural Industry:
AI 77B is used as a pest control agent for managing insect and mite infestations on various crops. Its application reason is to protect crops such as cotton, citrus fruits, and vegetables from damage caused by these pests, ensuring healthier and more productive harvests.
AI 77B is used as a surface-acting insecticide for disrupting the nervous system of insects and mites, leading to their paralysis and death. This is crucial for maintaining crop health and preventing yield losses due to pest damage.

InChI:InChI=1/C20H28N2O8/c1-9(2)6-12(22-19(28)18(27)17(26)11(21)8-15(24)25)14-7-10-4-3-5-13(23)16(10)20(29)30-14/h3-5,9,11-12,14,17-18,23,26-27H,6-8,21H2,1-2H3,(H,22,28)(H,24,25)/t11-,12-,14-,17-,18-/m0/s1

Upstream product

• 118918-76-6 (2S,5R)-2-phenyl-1-aza-3-oxabicyclo<3.3.0>octan-8-one 
• 118867-99-5 (2S,5R)-2-phenyl-1-aza-3-oxabicyclo<3.3.0>oct-6-en-8-one 
• 118868-02-3 (3S,4S,5S)-3,4-(isopropylidene)dioxy-2-hydroxymethylpyrrolidin-1-one 
• 118868-03-4 4-amino-5-C-cyano-4,5-dideoxy-2,3-O-isopropylidene-L-ribono-1,4-lactam 
• 118868-04-5 (3S,4S,5S)-N-(tert-butoxycarbonyl)-3,4-(isopropylidene)dioxy-2-cyanomethyl-pyrrolidin-1-one 
• 118868-01-2 (2S,5R,6S,7S)-2-phenyl-6,7-(isopropylidene)dioxy-1-aza-3-oxabicyclo<3.3.0>octan-8-one 
• 118868-05-6 (2S,3S,4S)-2,3-(isopropylidene)dioxy-4-(N-tert-butoxycarbonyl)amino-5-cyanopentanoic acid 
• 118868-00-1 (2S,5R,6S,7S)-2-phenyl-6,7-dihydroxy-1-aza-3-oxabicyclo<3.3.0>octan-8-one 
• 118867-98-4 (3S)-3-<(1S)-N-tert-butoxycarbonylamino-3-methylbutyl>-8-methoxymethyloxy-3,4-dihydroxyisocoumarin 
• 6893-26-1 D-Glutamic acid 
• 66673-40-3 (R)-5-hydroxymethylpyrrolidin-2-one 
• 68766-96-1 ethyl (R)-2-pyrrolidone-5-carboxylate 
• 118868-06-7 ((S)-2-Cyano-1-{(4S,5S)-5-[(S)-1-((S)-8-hydroxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-ethyl)-carbamic acid tert-butyl ester 
• 77675-03-7 AI-77-G 

Downstream Products

• 61-90-5 L-leucine 
• 78683-77-9 <6-<<1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl>amino>-4,5-dihydroxy-6-oxo-3-hexanamido>ammonium chloride 
• 77675-03-7 6-<<1-(2-carboxy-3-hydroxyphenyl)-2-hydroxy-5-methylhex-3-yl>amino>-4,5-dihydroxy-6-oxo-3-ammoniohexanoate 
• 77675-03-7 AI-77-G 

Relevant academic research and scientific papers

Bacilosarcins A and B, novel bioactive isocoumarins with unusual heterocyclic cores from the marine-derived bacterium Bacillus subtilis

Two novel isocoumarins, bacilosarcins A (1) and B (2) were isolated from a culture broth of the marine-derived bacterium Bacillus subtilis TP-B0611. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic analyses and chemical conversions. Compound 1 possesses an unprecedented 3-oxa-6,9-diazabicyclo[3.3.1]nonane ring system while 2 has a 2-hydroxymorpholine moiety that is rare in nature. These compounds showed growth inhibition against barnyard millet.

Application of Pd-Catalyzed C-H Alkylation Reaction in Total Syntheses of Twelve Amicoumacin-Type Natural Products

Enantioselective total syntheses of 12 amicoumacin-type natural products are accomplished with a palladium(II)-catalyzed C-H alkylation as the key step to furnish the 3,4-dihydroisocoumarin scaffold. The target chemicals are assembled in a convergent prot

Total Synthesis of Originally Proposed and Revised Structure of Hetiamacin A

The first total synthesis of the originally proposed and correct structures of hetiamacin A has been accomplished via Wittig olefination and Sharpless asymmetric dihydroxylation reaction. These total syntheses culminated in the stereostructural confirmati

Total synthesis of bacilosarcins A and B

(Chemical Equation Presented) I want to ride my bicycle: The thermodynamic stability of nitrogen-containing heterocyclic ring systems is exploited in the first enantioselective total synthesis of bacilosarcins A and B, which has been achieved in simple tw

Stereoselective synthesis of pseudopeptide microbial agent AI-77-B.

[structure: see text]. An efficient and highly stereoselective synthesis of the gastroprotective natural product AI-77-B is described. The stereocenters of the hydroxy amino acid moiety were generated by an ester-derived titanium-enolate-mediated syn-aldo

Total synthesis of AI-77-B: Stereoselective hydroxylation of 4-alkenylazetidinones

A stereoselective synthesis of the anti-ulcer compound AI-77-B 1 is described. The 4-formylazetidinone 6 was converted into the 4-(Z)-alkene 23 using a phosphonate condensation, and dihydroxylation using osmium tetroxide and N-methylmorpholine W-oxide gav

A new enantioselective total synthesis of Al-77-B

(formula presented) An enantioselective total synthesis of Al-77-B (1), a gastroprotective substance isolated from a culture broth of Bacillus pumilus Al-77, was performed in high overall yield. In this synthesis, the dihydroisocoumarin part 14 and the di

A Total Synthesis of the Natural Enantiomer of the Gastroprotective Natural Products AI-77-B and Amicoumacin C hydrochloride

A total synthesis of the natural enantiomer of AI-77-B and amicoumacin C hydrochloride is described.

A Total Synthesis of AI-77-B

A short total synthesis of AI-77-B (1) is reported, which produces the natural enantiomer using S-leucine and S-aspartic acid as the optically active starting materials. Key words: Natural product; AI-77-B; gastroprotective; total synthesis; enantioselect