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3-(2,4-difluorophenoxy)propanoic acid, also known as fenofibric acid, is a fibric acid derivative with the molecular formula C12H9F2O3. It is a medication used to lower cholesterol and triglyceride levels in the blood by increasing the enzyme activity involved in the breakdown of fatty acids.
Used in Pharmaceutical Industry:
3-(2,4-difluorophenoxy)propanoic acid is used as a cholesterol-lowering medication for managing hyperlipidemia and other lipid disorders. It works by reducing the production of triglycerides and cholesterol, and is typically administered orally in the form of tablets or capsules. It is often used in conjunction with diet and exercise to enhance its effectiveness.
Used in Treatment of Liver or Kidney Disease Patients:
3-(2,4-difluorophenoxy)propanoic acid is used with caution in individuals with liver or kidney disease due to potential side effects such as stomach pain, nausea, and muscle pain. Its administration requires careful monitoring in these patient populations to ensure safety and efficacy.

777-28-6

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777-28-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 777-28-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,7 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 777-28:
(5*7)+(4*7)+(3*7)+(2*2)+(1*8)=96
96 % 10 = 6
So 777-28-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H8F2O3/c10-6-1-2-8(7(11)5-6)14-4-3-9(12)13/h1-2,5H,3-4H2,(H,12,13)

777-28-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2,4-difluorophenoxy)propanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:777-28-6 SDS

777-28-6Downstream Products

777-28-6Relevant academic research and scientific papers

Synthesis, determination of absolute configuration, and biological evaluation of spiro-fused thiadiazoline inhibitors of kinesin spindle protein (KSP)

Angeles, Angie R.,Yang, Liping,Dai, Chaoyang,Brunskill, Andrew,Basso, Andrea D.,Siddiqui, M. Arshad

supporting information; experimental part, p. 6236 - 6239 (2011/01/12)

A facile and highly convergent synthesis of biologically active spiro-fused thiadiazoline KSP inhibitors is reported. The highlights of the synthesis include the Michael reaction and cyclization of thiosemicarbazone to 1,3,4-thiadiazoline. This chemistry lends itself to the preparation of (+)-2, a potent and orally bioavailable anti-cancer agent, and to the development of a structure-activity relationship program.

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