777060-58-9Relevant academic research and scientific papers
2-Oxazol-5-ylethanones by consecutive three-component amidation-coupling- cycloisomerization (ACCI) sequence
Merkul, Eugen,Grotkopp, Oliver,Mueller, Thomas J. J.
experimental part, p. 502 - 507 (2009/06/18)
Substituted oxazol-5-ylethanones can be synthesized in a consecutive three-component sequence starting from propargylamine and various acid chlorides, both for amidation and cross-coupling. Therefore, this diversity-oriented one-pot approach to substitute
A new consecutive three-component oxazole synthesis by an amidation-coupling-cycloisomerization (ACCI) sequence
Merkul, Eugen,Mueller, Thomas J. J.
, p. 4817 - 4819 (2007/10/03)
A novel consecutive three-component synthesis of 1-(hetero)aryl-2-(2- (hetero)aryl-oxazol-5-yl) ethanones starting from propargyl amine and acid chlorides, both for amidation and cross-coupling, is based upon an amidation-coupling-cycloisomerization (ACCI
A practical method for oxazole synthesis by cycloisomerization of propargyl amides
Wipf, Peter,Aoyama, Yasunori,Benedum, Tyler E.
, p. 3593 - 3595 (2007/10/03)
(Chemical Equation Presented) 2,5-Disubstituted and 2,4,5-trisubstituted oxazol-5-yl carbonyl compounds were prepared in good yields by a mild SiO 2-mediated cycloisomerization of propargyl amides.
