777089-83-5

Upstream product

• 372-39-4 3,5-difluoroaniline 
• 777089-82-4 4-amino-2,6-difluorobenzaldehyde 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 777089-95-9 {3,5-Difluoro-4-[(1S,5R,6S)-3-(4-methoxy-benzyl)-3-aza-bicyclo[3.1.0]hex-6-yl]-phenyl}-carbamic acid benzyl ester 
• 881012-65-3 Methanesulfonic acid (1S,2S,3R)-2-(4-benzyloxycarbonylamino-2,6-difluoro-phenyl)-3-methanesulfonyloxymethyl-cyclopropylmethyl ester 
• 777089-88-0 [4-((1S,2R,3S)-2,3-Bis-hydroxymethyl-cyclopropyl)-3,5-difluoro-phenyl]-carbamic acid benzyl ester 
• 777089-86-8 (2E)-3-{2,6-difluoro-4-[(benzyloxycarbonyl)amino]phenyl}prop-2-enyl diazoacetate 
• 777089-89-1 ((1S,5R,6S)-3,5-Difluoro-4-3-thia-bicyclo[3.1.0]hex-6-yl-phenyl)-carbamic acid benzyl ester 
• 777089-85-7 benzyl 2,6-difluoro-4-[(1E)-3-hydroxyprop-1-enyl]phenylacrylate 
• 777089-84-6 ethyl (2E)-3-(4-{[(benzyloxy)carbonyl]amino}-2,6-difluorophenyl)acrylate 

Relevant academic research and scientific papers

Synthesis of aza-, oxa-, and thiabicyclo[3.1.0]hexane heterocycles from a common synthetic intermediate

(Chemical Equation Presented) An efficient and stereospecific approach to the synthesis of structurally constrained aza-, oxa-, and thiabicyclo[3.1.0] hexane heterocycles has been achieved through application of the intramolecular cyclopropanation reactio

ANTIMICROBIAL [3.1.0] BICYCLOHEXYLPHENYL-OXAZOLIDINONE DERIVATIVES AND ANALOGUES

The present invention provides certain [3.1.0] bicyclic oxazolidinone derivatives of Formula (I) or pharmaceutically acceptable salts or prodrugs thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, an