7772-86-3Relevant academic research and scientific papers
The application of the intermediate 2-methyl-glyco-[2,1-d]-2-oxazolines for glycoside synthesis
Pertel, Sergey S,Chirva, Vasily Ya,Kadun, Andrey L,Kakayan, Elena S
, p. 895 - 899 (2007/10/03)
The synthesis of 2-acylamino-2-deoxysugars 1,2-trans-glycosides is described via the oxazolinium salt generated from an O,N-acetylated 1,2-cis-glycosyl halide of 2-amino-2-deoxysugar under the conditions of halide-anion catalysis. This salt was then inter
Use of 2-pyridyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside as a glycosyl donor and methyl iodide as an activator for the synthesis of 1,2-trans-linked saccharides
Mereyala,Gurijala
, p. 277 - 280 (2007/10/02)
The authors report on the successful use of 2-pyridyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D- glucopyranoside as a glycosyl donor and methyl iodide as an activator for the synthesis of 1,2-trans-linked saccharides. This synthesis is significant because the 2-amino-2-deoxyglycopyranosides are important constituents of glycoproteins, glycolipids and glycoside antibiotics. All known for their biological functions like antigen-antibody reactions and in cell communication.
A NEW SYNTHESIS OF 1,2-TRANS-2-ACETAMIDO-2-DEOXYGLYCOPYRANOSIDES VIA 1,2-TRANS-2-DEOXY-2-IODOGLYCOSYL AZIDES
Lafont, Dominique,Guilloux, Pascal,Descotes, Gerard
, p. 61 - 74 (2007/10/02)
Trans-addition of iodoazide to the double bond of 3,4,6-tri-O-acetyl-1,5-anhydro-D-arabino-hex-1-enitol yielded 2-deoxy-2-iodoglycosyl azides, which are percursors of 1,2-trans-2-amino-2-deoxyglycopyranosides when treated by an alcohol in the presence of triphenylphosphine.
