7773-83-3

Usage

Uses

Used in Environmental Applications:
1-DODECANETHIOL is used as a precursor in the preparation method of environmentally-friendly oxygen-deficient titanium disulfide at carbon nanodisk photocatalytic material. This material is employed for the degradation of organic pollutants in wastewater treatment, contributing to the development of green and sustainable solutions for environmental protection.
Used in Chemical Synthesis:
1-DODECANETHIOL serves as a valuable intermediate in the synthesis of various organic compounds, including surfactants, detergents, and other specialty chemicals. Its reactivity with other molecules allows for the formation of new compounds with specific properties and applications.
Used in Analytical Chemistry:
Due to its unique chemical properties, 1-DODECANETHIOL can be used as a derivatizing agent in analytical chemistry. It can help in the detection, identification, and quantification of various compounds in complex samples, such as environmental and biological matrices.
Used in Pharmaceutical Industry:
1-DODECANETHIOL may have potential applications in the pharmaceutical industry, where it can be used as a building block for the synthesis of drug molecules or as a component in drug delivery systems. Its ability to form stable complexes with other molecules can be exploited for the development of novel therapeutic agents.

InChI:InChI=1/C22H46S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3

Upstream product

• 6938-66-5 1-Bromodocosane 
• 17356-08-0 thiourea 

Downstream Products

• 1392113-76-6 C₆₅H₁₂₁N₅O₁₈S 

Relevant academic research and scientific papers

Carotene as a molecular wire: Conducting atomic force microscopy

A conducting atomic force microscope was used to measure the electrical properties of carotenoid molecules attached to a gold electrode. The thiolated carotene molecules were embedded in insulating n-alkanethiol self-assembled monolayers. At a contact force of a few nanoNewtons, a carotenoid molecule behaves ohmically with a resistance of approximately 4.2 ± 0.7 GΩ, over a million times more conductive than an alkane chain of similar length. Modes of electron transport are discussed.

The Role of Intermolecular and Molecule-Substrate Interactions in the Stability of Alkanethiol Nonsaturated Phases on Au(111)

The structure and stability of alkanethiols self-assembled on Au(111) have been studied as a function of the molecular chain length by means of atomic force microscopy (AFM) and grazing incidence X-ray diffraction (GIXD). Below saturation, phases consisting of molecules with different tilt angles and periodicities are formed. Differences in the mechanical stability of these phases are revealed by AFM experiments and discussed in terms of the competition between intermolecular and molecule-substrate interactions as a function of chain length. For long molecules, intermolecular interactions play a dominant role which stabilizes the formation of closed packed 30° tilted (√3×√3)R30° structures. For short molecules, the van der Waals interaction with the gold substrate favors the formation of a 50° tilted phase in which the molecules are arranged in a rectangular configuration.

Grafting nitrilotriacetic groups onto carboxylic acid-terminated self-assembled monolayers on gold surfaces for immobilization of histidine-tagged proteins

In this paper, we report a common intermediate method to present nitrilotriacetic acid (NTA) groups on gold surfaces for immobilizing His-tagged proteins onto the surfaces, and a full characterization of self-assembled monolayers (SAMs) terminating in carboxylic acids [HS(CH2) 15COOH (C15-COOH), HS(CH2)11(OCH 2CH2)3-OCH2COOH (EG 3-COOH), and HS(CH2)11(OCH2CH 2)5OCH2COOH (EG5-COOH)] and coupling reactions of an NTA-containing primary amine [(1S)-N-(5-amino-1-carboxypentyl) iminodiacetic acid; NTA-NH2] with the carboxylic acid on surfaces. The lateral packing densities of the COOH-terminated SAMs were calculated to be 4.32 (for C15-COOH), 3.49 (for EG3-COOH), and 2.65 (for EG5-COOH) molecules/nm2. The packing densities were decreased by incorporating a relatively flexible ethylene glycol (EG) group into the backbone of alkanethiols and increasing the number of the EG groups in the backbone of alkanethiols. The NTA group was then attached by coupling NTA-NH2 with the COOH group on the surfaces, followed by a Ni(II) complexation. The coupling reaction was characterized by FT-IR spectroscopy, ellipsometry, and XPS, and the coupling efficiency ("yield") was estimated by comparing the experimentally determined N Is to S 2p (N/S) ratio of XPS data with the N/S ratio calculated for the functionalization of the SAMs presenting NTA-Ni(II): the coupling yields were 30% (for C15-COOH) and 25% (for EG3-COOH and EG5-COOH). Preliminary experiments on the binding of His-tagged proteins onto the surfaces were also performed.