77742-28-0

Basic information

• Product Name: 3-amino-3-pyridin-4-yl-propionic acid ethyl ester
• Synonyms: 3-amino-3-pyridin-4-yl-propionic acid ethyl ester
• CAS NO: 77742-28-0
• Molecular Formula: C10H14N2O2
• Molecular Weight: 194.23036
• EINECS: -0
• Mol File: 77742-28-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-amino-3-pyridin-4-yl-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-3-pyridin-4-yl-propionic acid ethyl ester(77742-28-0)
• EPA Substance Registry System: 3-amino-3-pyridin-4-yl-propionic acid ethyl ester(77742-28-0)

Safety Data

• Hazardous Substances Data: 77742-28-0(Hazardous Substances Data)

Usage

General Description

3-amino-3-pyridin-4-yl-propionic acid ethyl ester is a chemical compound with the molecular formula C10H14N2O2. It is an ethyl ester derivative of 3-amino-3-pyridin-4-yl-propionic acid, which is an amino acid analog. 3-amino-3-pyridin-4-yl-propionic acid ethyl ester is used in pharmaceutical research and development as a building block for the synthesis of various biologically active compounds, particularly those targeting the central nervous system. It may also have potential applications in the development of new drugs for the treatment of neurological disorders. However, further research is needed to fully understand its pharmacological properties and potential therapeutic uses.

Upstream product

• 70076-13-0 ethyl 3-amino-3-(4-pyridyl)propenoate 
• 872-85-5 pyridine-4-carbaldehyde 
• 100-48-1 pyridine-4-carbonitrile 

Downstream Products

• 444806-04-6 (S)-3-amino-3-(4-pyridyl)propanoic acid 
• 1213912-39-0 ethyl (R)-3-amino-3-(4-pyridyl)propanoate 
• 372144-22-4 3-((tert-butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid 

Relevant articles and documents

Self-assembly of Pd2L2 Metallacycles Owning Diversely Functionalized Racemic Ligands

We present herein the efficient palladium(II)-directed self-assembly in water of a series of nine new diversely functionalized metallacycles, owning hydroxy/alkoxycarbonyl/azidoalkyl exo pendant groups attached to ditopic N-monoalkyl/aryl-4,4′-bipyridinium/2,7-diazapyrenium ligands. The highly convergent and versatile synthetic route for the ligands uses the Zincke reaction between (dinitrophenyl)bipyridinium/diazapyrenium salts and racemic amines as the key step. The stereochemical outcome of the self-assembly of the Pd2L2 species is discussed on the basis of density functional theory quantum-chemical calculations.

Burkholderia cepacia lipase is an excellent enzyme for the enantioselective hydrolysis of β-heteroaryl-β-amino esters

The enantioselective (E >200) lipase PS-catalysed hydrolysis of β-heteroaryl-β-amino esters is described. The reactions were performed with H2O (0.5 equiv) in either diisopropyl ether or tert-butyl methyl ether at 25 °C. The resulting β-heteroaryl-substituted β-amino acid enantiomers were formed in high enantiomeric excess (ee ≥ 97%) and in good yield (≥40%).