77744-06-0

Usage

Uses

Used in Pharmaceutical Industry:
(2-bromophenyl)(pyridin-3-yl)methanone is used as a building block for the synthesis of pharmaceutical compounds, as it can be incorporated into the structure of various drugs to enhance their properties and effectiveness.
Used in Agrochemical Industry:
(2-bromophenyl)(pyridin-3-yl)methanone is used as a precursor in the development of agrochemicals, such as pesticides and herbicides, due to its potential to improve the efficacy and selectivity of these products.
Used in Materials Science:
(2-bromophenyl)(pyridin-3-yl)methanone is used as a component in the synthesis of advanced materials, such as polymers and composites, where its unique structure can contribute to improved properties and performance.
Note: The specific applications and uses of (2-bromophenyl)(pyridin-3-yl)methanone may vary depending on its exact structure and the methods used for its synthesis. Further research and testing may be required to fully understand its potential in various industries.

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 626-55-1 3-Bromopyridine 
• 89667-09-4 (2-bromophenyl)(pyridin-3-yl)methanol 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 108-86-1 bromobenzene 

Downstream Products

• 5424-19-1 3-Benzoylpyridine 
• 79362-53-1 3-(2-bromophenyl)-N-methyl-3-(pyridin-3-yl)-allylamine 
• 344557-51-3 3-[(E)-1-(2-Bromo-phenyl)-3-chloro-propenyl]-pyridine 
• 77744-33-3 3-(2-bromophenyl)-N,N-dimethyl-3-(pyridin-3-yl)-allylamine 
• 3882-46-0 5H-indeno[1,2-b]pyridin-5-one 
• 5061-91-6 9H-indeno(2,1-c)pyridin-9-one 
• 77744-12-8 1-(2-Bromophenyl)-1-(3-pyridyl)-2-propen-1-ol 
• 77744-34-4 [(Z)-3-(2-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine 
• 77744-20-8 Acetic acid 1-(2-bromo-phenyl)-1-pyridin-3-yl-allyl ester 

Relevant academic research and scientific papers

Intramolecular radical additions to pyridines

Intramolecular 6-exolendo-trig and 5-exo-trig cyclisations of aryl radical intermediates to the α-, β- P- and γ-carbons of pyridine have been shown to be facile processes at neutral pH. The tether conjoining the radical donor to the pyridine plays an important role in determining the outcome of the reaction. When a Z-alkene is used as a tether, ortho-cyclisation proceeds in good yield. A more complex course is followed when a saturated two carbon tether is employed, leading to products derived from hydrogen atom abstraction, ipso-cyclisation and ortho-cyclisation pathways. All attempts to effect 5-exolendo-trig cyclisations failed. Tributyltin hydride, tris(trimethylsilyl)silane, tris(trimethylsilyl)germane and, in part, samarium(II) iodide can each be employed as mediators of the reaction.

Synthesis of 3-Aryl-3-pyridylallylamines Related to Zimelidine via Palladium-Catalyzed Amination

Reaction of aryl pyridyl ketones 1 with vinylmagnesium bromide followed by acetylation of the products 2 with acetic anhydride/Et3N and with 4-(dimethylamino)pyridine (DMAP) as a catalyst gave acetates 3 in high yields.Treatment of acetates 3 with dimethylamine in the presence of a palladium catalyst produced a mixture of E and Z isomers of 3-aryl-3-pyridylallylamines 4.