77746-89-5

Basic information

• Product Name: Benzamide, N-(1-phenyl-1H-pyrazol-5-yl)-
• CAS NO: 77746-89-5
• Molecular Formula: C16H13N3O
• Molecular Weight: 263.299
• Mol File: 77746-89-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(1-phenyl-1H-pyrazol-5-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(1-phenyl-1H-pyrazol-5-yl)-(77746-89-5)
• EPA Substance Registry System: Benzamide, N-(1-phenyl-1H-pyrazol-5-yl)-(77746-89-5)

Safety Data

• Hazardous Substances Data: 77746-89-5(Hazardous Substances Data)

Upstream product

• 826-85-7 1-phenylpyrazol-5-amine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 77746-55-5 N'-(4-Formyl-2-phenyl-2H-pyrazol-3-yl)-N,N-dimethyl-formamidine; hydrochloride 
• 77746-71-5 N,N-Dimethyl-N'-(2-phenyl-2H-pyrazol-3-yl)-formamidine 

Relevant articles and documents

VILSMEIER-HAACK REACTION OF 5-AMINO- AND 5-ACYLAMINO-PYRAZOLES

The Vilsmeier-Haack reaction of 5-aminopyrazole derivatives 1 was investigated in view of contradictory literature reports.Structure 2 of the products was proved both chemically and spectroscopically.The mechanism of the reaction was postulated on the basis of isolated intermediates 7 and 8. 5-Acylaminopyrazoles 9, 10 and 11 were found to give also 2 (and 7) under the Vilsmeier conditions by an acyl splitting reaction, proceeding probably via diacylamino derivatives 12.Compounds 2 provided a simple route to pyrazolopyrimidine derivatives 13 and 14 as well as to azomethine compounds 15-18.