77755-02-3Relevant academic research and scientific papers
A New Synthesis of Rutecarpine
Moehrle, Hans,Kamper, Christa,Schmid, Renate
, p. 990 - 995 (1980)
1,2,3,4-Tetrahydro-β-carboline (1) reacts with 2-nitrobenzyl chloride to yield the tertiary amine 2, which on reduction of the nitro group and dehydrogenating cyclization yields the pentacyclic amidine 4.Oxidation of 4 produces a mixture of rutecarpine (5) and the dehydrogenation compound 6, which are separated by chromatography.
