Archiv der Pharmazie p. 990 - 995 (1980)
Update date:2022-08-02
Topics:
Moehrle, Hans
Kamper, Christa
Schmid, Renate
1,2,3,4-Tetrahydro-β-carboline (1) reacts with 2-nitrobenzyl chloride to yield the tertiary amine 2, which on reduction of the nitro group and dehydrogenating cyclization yields the pentacyclic amidine 4.Oxidation of 4 produces a mixture of rutecarpine (5) and the dehydrogenation compound 6, which are separated by chromatography.
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Beijing Wisdom Chemicals Co., Ltd.
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Doi:10.1016/S0022-1139(00)85253-7
(1981)Doi:10.1002/zaac.200500526
(2006)Doi:10.1021/jm049917p
(2004)Doi:10.1016/j.tetlet.2008.08.056
(2008)Doi:10.1021/ic00132a007
(1982)Doi:10.1246/bcsj.54.1261
(1981)
