77756-14-0

Upstream product

• 61227-48-3 [(3-methoxyphenyl)methyl]propanedioic acid diethyl ester 
• 77756-13-9 2-<(3-methoxyphenyl)methyl>-1,3-propanediol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 76543-15-2 (-)-enterolactone 
• 77756-17-3 trans-2,3-bis(3-methoxybenzyl)-4-butanolide 
• 77756-17-3 2,3-bis(3-methoxybenzyl)-4-butanolide 
• 80704-91-2 (3R,4R)-3,4-bis<(3-methoxyphenyl)methyl>dihydro-2(3H)-furanone 
• 76543-16-3 2,3-bis(3-hydroxybenzyl)-butane-1,4-diol 
• 77756-23-1 Meso-2,3-bis-[(3-hydroxyphenyl)methyl]-1,4-butane diol 
• 76543-15-2 trans-2,3-bis[(3-hydroxyphenyl)methyl]-γ-butyrolactone 
• 76543-15-2 (3S,4R)-3,4-Bis-(3-hydroxy-benzyl)-dihydro-furan-2-one 
• 77756-19-5 (R)-4-<(3-methoxyphenyl)methyl>dihydro-2(3H)-furanone 
• 86653-16-9 4-<(3-methoxyphenyl)methyl>dihydrofuran-2(3H)-one 
• 77756-18-4 (R)-3-Hydroxymethyl-4-(3-methoxy-phenyl)-butyric acid 
• 77756-15-1 3-Hydroxymethyl-4-(3-methoxy-phenyl)-butyronitrile 

Relevant academic research and scientific papers

SYNTHESIS OF COMPOUND X, A NON-STEROIDAL CONSTITUENT OF FEMALE URINE, AND CONGENERS

The synthesis of trans-(+/-)- and (-)-3,4-bisdihydro-2-(3H)-furanone (1), a recently discovered constituent of female urine, and some related compounds of biological interest is described.

SYNTHESIS OF 13C-LABELLED ESTROGEN ANALOGUES

There is provided a method of producing novel 13C-labelled estrogen analogues. The method preferably proceeds via an intermediate A or B or which is a mixture of (A) or (B): wherein a13C atom is located at one or more of positions 1, 2, 3 or 4 and wherein R is an optionally substituted alkane, alkene, alkyne or aryl group. Preferably R is -CH2Ph. An alternative preferred intermediate compound is 13C-resorcinol.