77756-23-1

Upstream product

• 76543-15-2 (3S,4R)-3,4-Bis-(3-hydroxy-benzyl)-dihydro-furan-2-one 
• 61227-48-3 [(3-methoxyphenyl)methyl]propanedioic acid diethyl ester 
• 77756-14-0 Toluene-4-sulfonic acid 2-hydroxymethyl-3-(3-methoxy-phenyl)-propyl ester 
• 86653-16-9 4-<(3-methoxyphenyl)methyl>dihydrofuran-2(3H)-one 
• 78032-15-2 Acetic acid 3-[(3S,4S)-4-(3-acetoxy-benzyl)-2,5-dioxo-tetrahydro-furan-3-ylmethyl]-phenyl ester 
• 76543-15-2 trans-2,3-bis[(3-hydroxyphenyl)methyl]-γ-butyrolactone 
• 96995-00-5 3-benzyloxybenzaldehyde bis(phenylthio) acetal 
• 96995-01-6 (+/-)-trans-2-(3-benzyloxybenzyl)-3-<3-benzyloxy-α,α-bis(phenylthio)benzyl>butyrolactone 
• 1700-37-4 3-Benzyloxybenzaldehyde 
• 78032-12-9 3'-benzyloxybenzylidene succinic acid 
• 78032-13-0 2-[1-(3-Benzyloxy-phenyl)-meth-(Z)-ylidene]-succinic acid dimethyl ester 
• 77545-17-6 bis-(3'-benzyloxybenzylidene)-succinic acid 
• 77756-17-3 trans-2,3-bis(3-methoxybenzyl)-4-butanolide 
• 77756-15-1 3-Hydroxymethyl-4-(3-methoxy-phenyl)-butyronitrile 

Relevant academic research and scientific papers

Oxidative cyclisation of 3,4-dibenzyltetrahydrofurans using ruthenium tetra(trifluoroacetate)

A series of trans-3,4-dibenzyltetrahydrofurans has been synthesised and subjected to oxidative cyclisation using ruthenium tetra(trifluoroacetate), affording dibenzocyclooctadiene lignans belonging to the isostegane series, in high yields. Since no evidence was found for the formation of the corresponding stegane isomers it is assumed that the reactions proceed with complete diastereoselectivity.

Oxidative metabolism of the mammalian lignans enterolactone and enterodiol by rat, pig, and human liver microsomes

Hepatic microsomes from aroclor-treated male Wistar rats biotransform enterolactone to 12 metabolites, six of which carry an additional hydroxy group at the aromatic and six at the aliphatic moiety according to HPLC/MS and GC/MS analysis. The aromatic hyd

2,3-Bis-hydroxybenzyl-derivatives

The invention relates to compounds of the formula: STR1 in which R1 and R2 are the same or different groups selected from hydrogen or acyl or R1 and R2 together may represent an acetal group, and X and Y are the

CHEMICAL SYNTHESIS OF THE FIRST LIGNANS TO BE FOUND IN HUMANS AND ANIMALS

Trans-2,3-bis-(3'-hydroxybenzyl)-butyrolactone (1) and 2,3-bis-(3'-hydroxybenzyl)-butane-1,4-diol (2), recently identified in urine, have been synthesised in racemic form.

SYNTHESIS OF COMPOUND X, A NON-STEROIDAL CONSTITUENT OF FEMALE URINE, AND CONGENERS

The synthesis of trans-(+/-)- and (-)-3,4-bisdihydro-2-(3H)-furanone (1), a recently discovered constituent of female urine, and some related compounds of biological interest is described.