77782-90-2

Upstream product

• 1137089-32-7 (+)-(7S)-sydonic acid 
• 82188-73-6 (2S,3S)-2,3-epoxygeraniol 
• 1461710-33-7 C₁₀H₁₉ClO 
• 106-24-1 Geraniol 
• 1461710-35-9 (S)-4,8-dimethylnon-2-yne-1,4-diol 
• 1461710-37-1 (S,E)-4,8-dimethylnon-2-ene-1,4-diol 
• 108005-72-7 ((2S,3S)-3-methyl-3-(4-methylpentyl)oxiran-2-yl)methanol 
• 1461710-43-9 C₂₃H₄₀O₄Si 
• 1073897-13-8 (+)-2-(1-hydroxy-1,5-dimethylhexyl)-5-(2-trimethylsilylethoxymethoxymethyl)phenol 

Downstream Products

• 1073897-07-0 (+)-2-(1-hydroxy-1,5-dimethylhexyl)-5-tertbutyldimethylsiloxymethylphenol 

Relevant academic research and scientific papers

Isolation and absolute stereochemistry of optically active sydonic acid from Glonium sp. (Hysteriales, Ascomycota)

Optically active sydonic acid (1) was isolated for the first time from a culture broth of Glonium sp. The absolute stereochemistry was established to be (S) by comparing the circular dichroism (CD) spectrum with that of (+)-curcutetraol after conversion i

A divergent and stereoselective approach to phenolic 1,7-dihydroxy- bisabolane sesquiterpenes: Asymmetric total synthesis of (+)-curcutetraol, (+)-sydonol, (+)-sydonic acid, and (+)-7-O-methylsydonic acid

The combined use of the Sharpless asymmetric epoxidation, a number of stereospecific chemical transformations, and the 3,5-hexadienoic acid benzannulation protocol allowed us to devise a new, divergent, and stereoselective approach to terpenes with a chir

Asymmetric total synthesis of (+)-curcutetraol and (+)-sydonol

The asymmetric total syntheses of (+)-curcutetraol and (+)-sydonol, phenolic bisabolane-type sesquiterpenoids having chiral tertiary alcohol moiety in the o-position of a phenol, were achieved in high enantiomeric excesses (99% ee). The chiral tertiary benzylic alcohol moiety of these compounds was constructed by an asymmetric synthesis using an easily available chiral aminal, (-)-(2R,5S)-2-methoxycarbonyl-3-phenyl-1,3-diazabicyclo[3.3.0]octane. The absolute configurations of both (+)-curcutetraol and?(+)-sydonol have been assumed to be S-configuration based on the stereochemical course of the well established asymmetric synthesis used in the syntheses.