777859-74-2

Basic information

• Product Name: Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester
• Synonyms: Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester;2-Bromo-6-bromomethyl-benzoic acid methyl ester;METHYL 2-BROMO-6-(BROMOMETHYL)BENZOATE;ethyl 2-bromo-6-(bromomethyl)benzoate
• CAS NO: 777859-74-2
• Molecular Formula: C₉H₈Br₂O₂
• Molecular Weight: 307.96662
• Mol File: 777859-74-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester(777859-74-2)
• EPA Substance Registry System: Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester(777859-74-2)

Safety Data

• Hazardous Substances Data: 777859-74-2(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 2-bromo-6-(bromomethyl)-, methyl ester is a chemical compound with the molecular formula C9H8Br2O2. It is a methyl ester derivative of benzoic acid and contains two bromine atoms. Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block for the synthesis of various organic compounds in the chemical industry. Benzoic acid, 2-bromo-6-(bromomethyl)-, methyl ester is a colorless to pale yellow liquid with a pungent odor and is flammable. It is important to handle this compound with caution and follow proper safety protocols when working with it in a laboratory or industrial setting.

Upstream product

• 99548-56-8 methyl 2-bromo-6-methyl-benzoate 
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Downstream Products

• 200049-46-3 7-bromo-2,3-dihydro-1H-isoindol-1-one 
• 200049-49-6 7-(4-Fluoro-phenyl)-2,3-dihydro-isoindol-1-one 
• 1261277-01-3 C₂₅H₂₀ClN₃O₂ 
• 1261277-83-1 7-bromo-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)isoindolin-1-one 
• 1417188-96-5 7-(4-Fluorophenyl)-2-(2-thieno[3,2-b]pyridin-5-ylethyl)isoindolin-1-one 
• 1056950-89-0 2-bromo-6-formyl-benzoic acid methyl ester 
• 1021439-93-9 7-bromo-2-(4-t-butyl-phenyl)-2,3-dihydro-isoindol-1-one 

Relevant articles and documents

ISOINDOLINES AS HDAC INHIBITORS

The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs), having the formula: (I) wherein Z, X1, X2, Y1, Y2, Y3, L, Z, and R are described herein.

NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A

The present invention relates to novel carboxamide compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating or controlling medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders

Substituted heterocyclic compounds and methods of use

The present invention relates to compounds having the general formula or a pharmaceutically acceptable salt thereof, wherein R1 is a saturated or unsaturated 5-, 6- or 7-membered, ring containing 0, 1, 2 or 3 atoms selected from N, 0 and S, wherein the ring may be fused with a benzo group, and is substituted by 0, 1 or 2 oxo groups, and wherein R1 is additionally substituted; and R2 is a substituted C1-6alkyl. Also included is a method of prophylaxis or treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.