99548-56-8

Basic information

• Product Name: Methyl 2-bromo-6-methylbenzoate
• Synonyms: 2-BROMO-6-METHYLBENZOIC ACID METHYL ESTER;Methyl 2-bromo-6-methylbenzoate;Methyl 6-bromo-o-toluate, 3-Bromo-2-(methoxycarbonyl)toluene;Benzoic acid, 2-broMo-6-Methyl-, Methyl ester
• CAS NO: 99548-56-8
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07
• Product Categories: Aromatic Esters;Pharmaceutical intermediate
• Mol File: 99548-56-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 254.288 °C at 760 mmHg
• Flash Point: 107.59 °C
• Appearance: /
• Density: 1.434 g/cm³
• Storage Temp.: Room temperature.
• CAS DataBase Reference: Methyl 2-bromo-6-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-bromo-6-methylbenzoate(99548-56-8)
• EPA Substance Registry System: Methyl 2-bromo-6-methylbenzoate(99548-56-8)

Safety Data

• Hazardous Substances Data: 99548-56-8(Hazardous Substances Data)

Usage

General Description

Methyl 2-bromo-6-methylbenzoate is a chemical compound with the molecular formula C9H9BrO2. It is a methyl ester derivative of 2-bromo-6-methylbenzoic acid, containing a bromine atom and a methyl group. Methyl 2-bromo-6-methylbenzoate is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in organic chemistry reactions, such as esterification and bromination. Methyl 2-bromo-6-methylbenzoate is a colorless to pale yellow liquid with a pungent odor and is considered to be hazardous if ingested, inhaled, or absorbed through the skin. It should be handled with caution and in accordance with proper safety protocols.

Upstream product

• 67-56-1 methanol 
• 535961-79-6 2-bromo-6-methylbenzoyl chloride 
• 61940-22-5 methyl 2-methyl-6-nitrobenzoate 
• 90259-31-7 2-bromo-6-methylbenzoic acid 
• 74-88-4 methyl iodide 
• 4389-50-8 2-amino-6-methylbenzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 13506-76-8 2-methyl-6-nitrobenzoic acid 
• 18595-13-6 2-amino-6-methylbenzoic acid methyl ester 

Downstream Products

• 777859-74-2 methyl?2-bromo-6-(bromomethyl)benzoate 
• 872373-57-4 2-(2-methoxy-6-vinylphenoxy)-6-methylbenzoic acid 
• 872373-60-9 (7S,8R,9E)-14-methoxy-8-(4-methoxyphenoxy)-4-methyl-7-pentyl-7,8-dihydro-5H-dibenzo[b,j]dioxacycloundecin-5-one 
• 127510-98-9 methyl 2-cyano-6-methylbenzoate 
• 1417188-96-5 7-(4-Fluorophenyl)-2-(2-thieno[3,2-b]pyridin-5-ylethyl)isoindolin-1-one 
• 1172117-25-7 2-methyl-6-vinylbenzoic acid 
• 1022980-69-3 methyl 2-(bromomethyl)-6-cyanobenzoate 

Relevant articles and documents

ISOINDOLINES AS HDAC INHIBITORS

The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs), having the formula: (I) wherein Z, X1, X2, Y1, Y2, Y3, L, Z, and R are described herein.

NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A

The present invention relates to novel carboxamide compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating or controlling medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders

Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Through conformational restriction of a benzamide by formation of a seven-membered hydrogen-bond with an oxindole carbonyl group, a series of PARP inhibitors was designed for appropriate orientation for binding to the PARP surface. This series of compound