77800-69-2

Upstream product

• 77800-65-8 7-Ethoxy-5-ethoxycarbonyl-6-hydroxy-2,3-diphenyl-4H-azepine 
• 60769-85-9 rel-(1S,5R,7R)-5-ethoxycarbonyl-1,7-diphenyl-2-azabicyclo<3.2.0>heptane-3,4-dione 
• 77800-62-5 dl-(1R*,5S*,7S*)-3-ethoxy-5-ethoxycarbonyl-1,7-diphenyl-2-azabicyclo<3.2.0>hept-2-en-4-one 
• 73197-57-6 4-Ethoxycarbonyl-3-hydroxy-6,7-diphenyl-1,5-dihydro-2H-azepin-2-one 
• 60769-85-9 rel-(1S,5R,7S)-5-ethoxycarbonyl-1,7-diphenyl-2-azabicyclo<3.2.0>heptane-2,4-dione 
• 122184-91-2 dl.(1R*,5S*)-5-Ethoxycarbonyl-1,7-diphenyl-2-azabicyclo<3.2.0>hept-6-ene-3,4-dione 
• 77800-62-5 (1R,5S)-3-Ethoxy-4-oxo-1,7-diphenyl-2-aza-bicyclo[3.2.0]hept-2-ene-5-carboxylic acid ethyl ester 
• 59046-34-3 3-ethoxycarbonyl-2-phenyldioxopyrroline 

Downstream Products

• 67171-74-8 Ethyl 3-ethoxycarbonyl-5,6-diphenylpyridine-2-carboxylate 

Relevant academic research and scientific papers

2-AZABICYCLOHEPTANE-3,4-DIONES (3): LEWIS ACID CATALYSED RING EXPANSION OF 3-ETHOXY-Δ2-AZABICYCLOHEPTAN-4-ONES: SYNTHESIS OF 2-ETHOXY-3-AZATROPONES

Treatment of 2-azabicycloheptane-3,4-dione imidic ester (6) with tin(IV) chloride gave the dihydroazatropolone 2-ethyl ethers (7) in moderate yields which were also obtained by reaction of dihydroazatropolones (2) with Meerwein reagent.DDQ oxidation of 7 gave 2-ethoxy-3-azatropones (8), which rearranged, on treatment with water, into ethyl pyridine 2-carboxylate (10).Spectroscopic data of azatropolone 2-ethyl ethers were also described.