77820-60-1 Usage
Class
Organic compound, specifically a ketone
Structure
A carbonyl group bonded to a phenyl group and an isoindoline ring
Applications
Pharmaceutical and chemical industries, as a reagent in organic synthesis, a building block for creating other compounds, and as a research tool in organic chemistry and drug development
Versatility
Potential applications in various industrial and scientific fields
Check Digit Verification of cas no
The CAS Registry Mumber 77820-60-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,8,2 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77820-60:
(7*7)+(6*7)+(5*8)+(4*2)+(3*0)+(2*6)+(1*0)=151
151 % 10 = 1
So 77820-60-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO/c1-12(18)13-6-8-16(9-7-13)17-10-14-4-2-3-5-15(14)11-17/h2-9H,10-11H2,1H3
77820-60-1Relevant articles and documents
Oxidative Desymmetrization of Isoindolines Realized by tert -Butyl Nitrite (TBN) Initiated Radical sp 3C-H Activation Relay (CHAR)
Sun, Zheng,Shao, Yu,Zhang, Shuwei,Zhang, Yuxian,Yuan, Yu,Jia, Xiaodong
, p. 1663 - 1671 (2021/02/01)
An oxidative desymmetrization of isoindolines was realized by TBN initiated radical sp 3C-H activation relay (CHAR), providing a series of ω-hydroxylactams in high yields. This reaction exhibits broad substrate scope and functional group tolerance, and even N -alkyl iso-indolines can be well tolerated. The mechanistic study shows that the C-H bond oxidation, dioxygen trapping and intramolecular 1,5-H shift might be the key steps to achieve the oxidative desymmetrization.
