77846-07-2Relevant academic research and scientific papers
COMPOUNDS FOR TREATMENT OF GLIOBLASTOMA
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Paragraph 00258; 00354-00355, (2018/09/08)
The present invention relates to compounds and methods for the treatment of glioblastoma, as well as to a pharmaceutical composition comprising said compounds. More specifically the invention relates to substituted quinoline derivatives having the formula (I), (II) or (III), and a pharmaceutical composition comprising said compounds for the treatment of cancer. (Formulae (I), (II), (III))
Synthesis of substituted isatins
Klein, Larry L.,Tufano, Michael D.
supporting information, p. 1008 - 1011 (2013/02/25)
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules
On the scope of diastereoselective allylation of various chiral glyoxylic oxime ethers with allyltributylstannane in the presence of?a Lewis acid and triallylaluminum
Kulkarni, Neelesh A.,Yao, Ching-Fa,Chen, Kwunmin
, p. 7816 - 7822 (2008/02/07)
The nucleophilic allylation of various chiral auxiliaries derived glyoxylic oxime ethers was studied. The use of allyltributylstannane in the presence of a Lewis acid and triallylaluminum provided the corresponding homoallylic amines in high chemical yiel
