778560-53-5

Basic information

• Product Name: (S)-2-{[(S)-3-(3-Benzyloxy-2-chloro-4-methoxy-phenyl)-2-methylamino-propionyl]-methyl-amino}-3-phenyl-propionic acid allyl ester
• Synonyms: (S)-2-{[(S)-3-(3-Benzyloxy-2-chloro-4-methoxy-phenyl)-2-methylamino-propionyl]-methyl-amino}-3-phenyl-propionic acid allyl ester
• CAS NO: 778560-53-5
• Molecular Weight: 551.082
• Mol File: 778560-53-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{[(S)-3-(3-Benzyloxy-2-chloro-4-methoxy-phenyl)-2-methylamino-propionyl]-methyl-amino}-3-phenyl-propionic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{[(S)-3-(3-Benzyloxy-2-chloro-4-methoxy-phenyl)-2-methylamino-propionyl]-methyl-amino}-3-phenyl-propionic acid allyl ester(778560-53-5)
• EPA Substance Registry System: (S)-2-{[(S)-3-(3-Benzyloxy-2-chloro-4-methoxy-phenyl)-2-methylamino-propionyl]-methyl-amino}-3-phenyl-propionic acid allyl ester(778560-53-5)

Safety Data

• Hazardous Substances Data: 778560-53-5(Hazardous Substances Data)

Upstream product

• 53713-77-2 3-benzyloxy-2-chloro-4-methoxy-benzaldehyde 
• 220903-33-3 (S)-N-tert-butyloxycarbonyl-(3-benzyloxy-2-chloro-4-methoxy)-phenylalanine ethyl ester 
• 210105-85-4 (S)-N-tert-butyloxycarbonyl-N-methyl-(3-benzyloxy-2-chloro-4-methoxy)-phenylalanine 
• 220903-34-4 (S)-N-tert-butyloxycarbonyl-(3-benzyloxy-2-chloro-4-methoxy)-phenylalanine 
• 210105-82-1 3-benzyloxy-2-chloro-4-methoxybenzyl bromide 
• 110038-82-9 3-benzyloxy-2-chloro-4-methoxybenzyl alcohol 
• 37687-57-3 2-chloro-3-hydroxy-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 
• 220903-37-7 N-tert-butyloxycarbonyl-N-methyl-(3-benzyloxy-2-chloro-4-methoxy)-(S)-phenylalanyl-N-methyl-(S)-phenylalanine allyl ester 

Downstream Products

• 210105-90-1 N-benzyloxycarbonyl-(O-benzyloxycarbonyl)-(R)-tyrosyl-N-methyl-(3-benzyloxy-2-chloro-4-methoxy)-(S)-phenylalanyl-N-methyl-(S)-phenylalanine allyl ester 
• 147317-36-0 pepticinnamin E 
• 210105-95-6 N-benzyloxycarbonyl-(O-benzyloxycarbonyl)-(R)-tyrosyl-N-methyl-(3-benzyloxy-2-chloro-4-methoxy)-(S)-phenylalanyl-N-methyl-(S)-phenylalanine 
• 210105-92-3 N-benzyloxycarbonyl-(O-benzyloxycarbonyl)-(R)-tyrosyl-N-methyl-(3-benzyloxy-2-chloro-4-methoxy)-(S)-phenylalanyl-N-methyl-(S)-phenylalanine-(R)-(piperazine-2,5-dione)methyl ester 

Relevant articles and documents

Synthesis and in vitro evaluation of the Ras farnesyltransferase inhibitor pepticinnamin E

A modularly built bisubstrate inhibitor, the natural product pepticinnamin E (shown on the right) was synthesized for the first time. In the case of in vitro assays it inhibits the enzyme farnesyltransferase with respect to both the peptide substrate and farnesylpyrophosohate (K1 = 30 and 8 μM, respectively). The inhibitory activity is decisively influenced by the central tripeptide unit and the absolute configuration of the non-proteinogenic amino acid incorporated therein.