778581-74-1Relevant articles and documents
Aza bicycloderivative, preparation and application thereof
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Paragraph 0155; 0156; 0158, (2019/04/27)
The invention discloses an aza bicycloderivative, preparation and an application thereof. The aza bicycloderivative has a structure shown in formula I, wherein the definition of all substituted groupsis described in specification and claims. The compound
An approach to azabicyclo[ n.3.1]alkanes by double mannich reaction
Mityuk, Andrey P.,Denisenko, Aleksandr V.,Dacenko, Oleksandr P.,Grygorenko, Oleksandr O.,Mykhailiuk, Pavel K.,Volochnyuk, Dmitriy M.,Shishkin, Oleg V.,Tolmachev, Andrey A.
experimental part, p. 493 - 497 (2010/04/26)
Chlorotrimethylsilane-promoted double Mannich annulation of ketones using N,N-bis(methoxymethyl)benzylamine has been explored. It has been shown that the structure of the substrate drastically influenced the outcome of the reaction. The method allows azabicyclo[n.3.1]alkane derivatives (n=2-5) to be obtained in good yields. Georg Thieme Verlag Stuttgart New York.