778628-31-2Relevant articles and documents
Iron-catalyzed kinetic resolution of N-sulfonyl oxaziridines
Williamson, Kevin S.,Sawicki, James W.,Yoon, Tehshik P.
, p. 3524 - 3527 (2014)
We have developed a highly selective kinetic resolution of N-sulfonyl oxaziridines. This reaction utilizes an inexpensive and easily synthesized iron bis(oxazoline) catalyst to promote the efficient rearrangement of oxaziridines to the corresponding N-sulfonyl imides; no sacrificial reagents are required to effect this resolution. This process is readily translated to gram scale, which provides a practical method for the preparation of structurally diverse, enantiopure N-sulfonyl oxaziridines for use as reagents in organic synthesis.
