77890-81-4

Basic information

• Product Name: Silane, [2-(3,4-dihydro-2H-pyran-2-yl)-1-(phenylthio)ethenyl]trimethyl-, (E)-
• CAS NO: 77890-81-4
• Molecular Formula: C16H22OSSi
• Molecular Weight: 290.502
• Mol File: 77890-81-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Silane, [2-(3,4-dihydro-2H-pyran-2-yl)-1-(phenylthio)ethenyl]trimethyl-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, [2-(3,4-dihydro-2H-pyran-2-yl)-1-(phenylthio)ethenyl]trimethyl-, (E)-(77890-81-4)
• EPA Substance Registry System: Silane, [2-(3,4-dihydro-2H-pyran-2-yl)-1-(phenylthio)ethenyl]trimethyl-, (E)-(77890-81-4)

Safety Data

• Hazardous Substances Data: 77890-81-4(Hazardous Substances Data)

Upstream product

• 100-73-2 acrolein dimer 
• 62762-44-1 lithium bis(trimethylsilyl)(phenylthio)methylide 

Downstream Products

• 82599-06-2 {5-[(2E,4E,11E)-(6R,9S,10S)-9-(tert-Butyl-dimethyl-silanyloxy)-6,7,7-trimethoxy-2,10,12-trimethyl-13-oxo-trideca-2,4,11-trienyl]-2-chloro-3-methoxy-phenyl}-methyl-carbamic acid methyl ester 
• 77943-81-8 {(Z)-1-Benzenesulfonyl-2-[(1R,2R,4R,6R)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]hept-4-yl]-vinyl}-trimethyl-silane 
• 77890-93-8 {(Z)-1-Benzenesulfonyl-2-[(1S,2R,4R,6S)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]hept-4-yl]-vinyl}-trimethyl-silane 
• 91422-78-5 {(Z)-1-Benzenesulfonyl-2-[(2S,6R)-6-(2-methoxy-ethoxy)-3,6-dihydro-2H-pyran-2-yl]-vinyl}-trimethyl-silane 
• 77943-80-7 {(Z)-1-Benzenesulfonyl-2-[(2S,6S)-6-(2-methoxy-ethoxy)-3,6-dihydro-2H-pyran-2-yl]-vinyl}-trimethyl-silane 
• 85621-27-8 (2E,4E,11E,13E)-(6S,7S,10R)-7-(tert-Butyl-dimethyl-silanyloxy)-15-[4-chloro-3-methoxy-5-(methoxycarbonyl-methyl-amino)-phenyl]-9,9,10-trimethoxy-4,6,14-trimethyl-pentadeca-2,4,11,13-tetraenoic acid methyl ester 
• 82599-05-1 {5-[(2E,4E,11E)-(6R,9S,10S)-9-(tert-Butyl-dimethyl-silanyloxy)-6,7,7,13,13-pentamethoxy-2,10,12-trimethyl-trideca-2,4,11-trienyl]-2-chloro-3-methoxy-phenyl}-methyl-carbamic acid methyl ester 
• 91365-95-6 (E)-3-{(2R,3R)-3-[(6E,8E)-(1R,2R,5S)-2-(tert-Butyl-dimethyl-silanyloxy)-10-(4-chloro-3-methoxy-5-methylamino-phenyl)-4,4,5-trimethoxy-1,9-dimethyl-deca-6,8-dienyl]-2-methyl-oxiranyl}-acrylic acid methyl ester 
• 85621-22-3 (E)-3-{(2S,3S)-3-[(6E,8E)-(1S,2S,5R)-2-(tert-Butyl-dimethyl-silanyloxy)-10-(4-chloro-3-methoxy-5-methylamino-phenyl)-4,4,5-trimethoxy-1,9-dimethyl-deca-6,8-dienyl]-2-methyl-oxiranyl}-acrylic acid 
• 85621-28-9 (2E,4E,11E,13E)-(6S,7S,10R)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(4-chloro-3-methoxy-5-methylamino-phenyl)-9,9,10-trimethoxy-4,6,14-trimethyl-pentadeca-2,4,11,13-tetraenoic acid 
• 82598-94-5 (2S,3S,4R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-3-methoxy-4-(4-methoxy-benzyloxy)-2-(2-methoxy-ethoxy)-tetrahydro-pyran 
• 82599-08-4 {(2S,3S)-3-[(6E,8E)-(1S,2S,5R)-2-(tert-Butyl-dimethyl-silanyloxy)-10-(4-chloro-3-methoxy-5-methylamino-phenyl)-4,4,5-trimethoxy-1,9-dimethyl-deca-6,8-dienyl]-2-methyl-oxiranyl}-methanol 
• 82599-15-3 (2R,3S)-3-[(6E,8E)-(1S,2S,5R)-2-(tert-Butyl-dimethyl-silanyloxy)-10-(4-chloro-3-methoxy-5-methylamino-phenyl)-4,4,5-trimethoxy-1,9-dimethyl-deca-6,8-dienyl]-2-methyl-oxirane-2-carbaldehyde 
• 82598-96-7 (3R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-benzenesulfonyl-ethoxy)-3,4,4-trimethoxy-tetrahydro-pyran 

Relevant articles and documents

SYNTHETIC STUDIES TOWARD MAYTANSINOIDS (2) A NEW STRATEGY BASED ON ASYMMETRIC INDUCTION BY HETEROCONJUGATE ADDITION OF METHYLLITHIUM ONTO PYRANOSYL HETERO-OLEFINS

The functionalized pyranosyl hetero-olefins 4a, 13 and 15 received a remarkable diastereoselective addition of methyllithium to form threo adducts, one of which was introduced into a possible synthetic intermediate as 3 for maytansine (1) along Scheme I.