77929-17-0

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 

Downstream Products

• 6389-79-3 (+)-(R)_p methyl methylphenylphosphinate 
• 65665-33-0 (+)-(R)_p Methyl ethylphenylphosphinate 
• 78177-46-5 (R)-(2-Hydroxymethyl-pyrrolidin-1-yl)-phenyl-phosphinic acid methyl ester 
• 77929-23-8 methyl (S)-(2-methoxyphenyl)(phenyl)phosphinate 
• 77929-21-6 (+)-(R)_p Methyl allylphenylphosphinate 
• 61733-60-6 (R)-O-ethyl O-methyl phenylphosphonothioate 

Relevant academic research and scientific papers

Enantioselective reduction of ketones by borane catalysed by oxazaphospholidine oxides

New enantioselective catalysts for the asymmetric reduction of ketones by borane are described. Easily prepared by oxidation of chiral oxazaphospholidines, these compounds increase sensitively the reduction rate of numerous ketones and induce ee's up to 94% in the case of the 2-chloroacetophenone.

4-Dimethylaminopyridine-catalyzed dynamic kinetic resolution in asymmetric synthesis of P-chirogenic 1,3,2-oxazaphospholidine-2-oxides

Excellent diastereoselectivity (dr value up to 100: 0) was achieved in DMAP-catalyzed P-N bond formation in the synthesis of P-chirogenic organophosphines from phenylphosphonic dichloride (PhP(O)Cl2) and (S)-2-pyrrolidinemethanol derivatives. I

New chiral phosphinamide catalysts for highly enantioselective reduction of ketones

A novel class of recoverable and highly stable phosphinamide catalysts for the asymmetric reduction of ketones by borane is described. Enantiomeric excesses of up to 92% have been obtained using 10 mol% of the optimum catalyst.

STEREOCHEMISTRY OF THE BASE-CATALYZED METHANOLYSIS OF 2-PHENYL-TETRAHYDROPYRROLO-1,3,2-OXAZAPHOSPHOLES

Diastereomerically pure bicyclic oxazaphospholes were prepared from L-prolinol and phenylphosphonic or thiophosphonic dichloride and their absolute configurations were determined based on the interpretation of NMR spectra.The base-catalyzed methanolysis o