Tetrahedron Letters p. 39 - 42 (1996)
Update date:2022-09-26
Topics:
Chiodi, Olivier
Fotiadu, Frederic
Sylvestre, Maud
Buono, Gerard
New enantioselective catalysts for the asymmetric reduction of ketones by borane are described. Easily prepared by oxidation of chiral oxazaphospholidines, these compounds increase sensitively the reduction rate of numerous ketones and induce ee's up to 94% in the case of the 2-chloroacetophenone.
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